Skin, eye and hair pigmentation requires a delicate balance of acidity within the cellular...
Combining two cutting-edge techniques reveals that neurons in the prefrontal cortex are built to...
It is not surprising that a good night’s sleep improves our ability to remember what we learned...
Scientists have developed a quicker and more efficient method to alter the genes of mice with CRISPR-Cas9, simplifying a procedure growing in popularity because of the ease of using the new gene-editing tool. The new method gets around a time-consuming bottleneck in creating knockout mice: using microscopic needles to inject gene-editing molecules into a fertilized egg.
An antibody, produced by the body's own immune system, preferentially attacks only cancer cells, according to a new study from researchers at Duke University Medical Center. It works by dismantling the cancer cell's defense system.
Scientists have identified a molecular key that breast cancer cells use to invade bone marrow in mice, where they may be protected from chemotherapy or hormonal therapies that could otherwise eradicate them.
A stress receptor in the brain is found to regulate metabolic responses to stressful situations differently in male and female mice.
When it comes to measuring brain activity, scientists have tools that can take a precise look at a small slice of the brain (less than one cubic millimeter), or a blurred look at a larger area. Now, researchers describe a new technique that combines the best of both worlds — it captures a detailed snapshot of global activity in the mouse brain.
The fruit fly Drosophila bifurca is only a few millimeters in size but produces sperm that are almost six centimeters long. A team of researchers now provides the first conclusive explanation for the evolution of such giant sperm.
Dogs are an excellent animal model for studying cancer, a recent study published in PLOS Genetics found. The research identified genes that could possibly play a role in the development of brain cancer in both dogs and humans.
Santa Cruz Biotechnology, Inc. has agreed to pay a $3.5 million fine, and revoke its research registration and dealer license in accordance with terms of a legal settlement with the U.S. Dept. of Agriculture.
A new molecular mechanism can be used to inhibit the growth of hepatocellular carcinoma, which is the most common liver cancer.
Unique connections in the adolescent brain make it possible to easily diminish fear memories and avoid anxiety later in life. The findings may have important implications for the treatment of trauma and anxiety disorders.
Researchers have developed a method of implanting cells to create a human bone-like structure in mice. This allows investigators to study a whole host of blood cancers and other diseases that they had trouble studying before.
Three canine genes for Caffey, Raine, and van den Ende-Gupta syndrome have been identified in a new study published in PLOS Genetics. These discoveries will help further the development of rare disease diagnostic and treatments, as well as veterinary diagnostics and breeding programs.
In a recent study, scientists identified a pathway through which transcription factor proteins regulate lymphangiogenesis, the formation of lymphatic vessels from pre-existing lymphatic vessels. These results suggest a new mechanism for diseases associated with lymphatic vessels, which transport fluid out of tissues as part of the body’s lymphatic system.
Chemistry has provided many key tools and techniques to the biological community in the last twenty years. We can now make proteins that Mother Nature never thought of, image unique parts of live cells and even see cells in live animals.
In a new study using mice and lab-grown human cells, a scientific team led by Johns Hopkins Kimmel Cancer Center researchers show how a triple-drug cocktail can shrink triple-negative breast cancers by killing off cancer cells and halting new tumor growth.