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The Lead

How Zebrafish Maintain a Steady Gaze

April 18, 2014 | by Max Planck Institute | Comments

Scientists have discovered an array of new types of neurons, which help the brain of zebrafish to perceive, and compensate for, self-motion.                               



Four TurnKey Conference Sessions Eligible for GBCI Credit

April 18, 2014 1:46 pm | Comments

Earn GBCI credit at the 2014 TurnKey Conference, held May 13-14 in National Harbor, MD by participating in one of the following sessions: Streamlining the Vivarium Facility Performance Verification Process, Are We There Yet? Bridging the Gap between Construction and Operation, Planning for the Unthinkable in Vivarium Design, and Facility Containment & Extreme Events: A Risk-Based Approach.


Innovative Strategy Facilitates Organ Repair

April 18, 2014 12:39 pm | by Inserm | Comments

A team of researchers has just demonstrated that the principle of adhesion by aqueous solutions of nanoparticles can be used in vivo to repair soft-tissue organs and tissues.                     


Nasal Spray Could Protect against Any Flu

April 17, 2014 1:40 pm | by Univ. of St. Andrews | Comments

Scientists have developed a novel treatment that could protect against current, future and even pandemic strains of flu. The preventative treatment could be used as a "frontline defence" before an effective flu vaccine is developed.     


Essential Protein Needed for Fertilization

April 17, 2014 1:25 pm | by Wellcome Trust Sanger Institute | Comments

Researchers have discovered interacting proteins on the surface of the sperm and the egg essential to begin mammalian life. These proteins, which allow the sperm and egg to recognize one another, offer new paths towards improved fertility treatments and the development of new contraceptives.


Cancer Drugs Block Dementia-linked Brain Inflammation in Mice

April 17, 2014 1:11 pm | by Univ. of California, Irvine | Comments

A class of drugs developed to treat immune-related conditions and cancer — including one currently in clinical trials for glioblastoma and other tumors — eliminates neural inflammation associated with dementia-linked diseases and brain injuries.


Cause of Eye Mobility Disorder Developed in Mouse Models

April 17, 2014 1:03 pm | by Steve Kehoe, Univ. of Iowa | Comments

Researchers have developed a mutated mouse model that mimics the human mutation of an eye mobility disorder in order to understand why it occurs.                             


TurnKey Session of the Week: Facility Containment & Extreme Events: A Risk-Based Approach

April 17, 2014 8:13 am | Comments

The major goal of a bio-containment operation is to maintain the primary and secondary facility containment systems, preventing the release of pathogenic material. During tornado events, extreme internal and external air pressure differentials will test the design parameters of structural and enclosure systems. This presentation will identify, compare, and define a risk-based approach to the most vulnerable of these systems.


UofL Has 25,000 Rodents on Its Health Sciences Campus (For Research)

April 16, 2014 3:31 pm | Comments

The University of Louisville's health sciences campus has thousands of rats and mice — and officials are not only OK with it, they're planning to soon get the rodents new homes through an allotment from the Kentucky General Assembly.   


Technique Reverse-engineers Developing Lung

April 16, 2014 1:08 pm | by Tom Abate, Stanford Univ. | Comments

In a feat of reverse tissue engineering, researchers have begun to unravel the complex genetic coding that allows embryonic cells to proliferate and transform into all of the specialized cells that perform a myriad of different biological tasks.  


Hair from Infant Monkeys Gives Clues about Life in the Womb

April 16, 2014 12:36 pm | by Kelly April Tyrrell, Univ. of Wisconsin-Madison | Comments

A team researchers show in a study of rhesus monkeys that hair can reveal the womb environment in which an infant formed.                                     


Mouse Model Would Have Predicted Toxicity of Fatal Drug

April 16, 2014 12:22 pm | by PLOS | Comments

Over 20 years after the fatal fialuridine trial, a study demonstrates that mice with humanized livers recapitulate the drug's toxicity.                                 


Why Does Eating Less Increase Life Span?

April 16, 2014 12:05 pm | by Annie Sneed, Scientific American | Comments

Nematode worms, fruit flies, mice and other lab animals live longer, healthier lives when they eat less than they otherwise would if more food were available. Researchers have declared the most popular theory doesn’t make evolutionary sense, and they’ve proposed a new explanation in its place.

'3D' Model Could Reduce Animal Testing of Asthma and Allergy Medications

April 16, 2014 9:40 am | by American Chemical Society | Comments

Scientists report that they’ve developed a simple, “3D” laboratory method to test asthma and allergy medications that mimics what happens in the body, which could help reduce the need for animal testing.             

Researchers Transplant Regenerated Esophagus in Rats

April 15, 2014 2:09 pm | by Karolinska Institutet | Comments

Tissue engineering has been used to construct natural esophagi, which in combination with bone marrow stem cells have been safely and effectively transplanted in rats.                        


Reversing Alzheimer's Symptoms in Mice

April 15, 2014 1:55 pm | by Deborah Halber, MIT | Comments

Limiting a certain protein in the brain reverses Alzheimer’s symptoms in mice. Researchers found that the overproduction of the protein known as p25 may be the culprit behind the sticky protein-fragment clusters that build up in the brains of Alzheimer's patients.



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