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The Lead

Fast-like Diet Could Reduce MS Symptoms

May 27, 2016 | by Emily Gersema, USC | Comments

Previous studies indicated that similar diets could fight cancer and reduce the signs of aging.


Researchers Develop Faster, Better CRISPR Editing in Mice

May 27, 2016 12:08 pm | by Robert Sanders, UC Berkeley | Comments

Scientists have developed a quicker and more efficient method to alter the genes of mice with CRISPR-Cas9, simplifying a procedure growing in popularity because of the ease of using the new gene-editing tool. The new method gets around a time-consuming bottleneck in creating knockout mice: using microscopic needles to inject gene-editing molecules into a fertilized egg.

Antibody Attacks Only Cancer Cells, Animal Study Shows

May 27, 2016 11:43 am | by Elizabeth Doughman, Editor-in-Chief | Comments

An antibody, produced by the body's own immune system, preferentially attacks only cancer cells, according to a new study from researchers at Duke University Medical Center. It works by dismantling the cancer cell's defense system.


Breast Cancer Cells Lose Hide-and-Seek Game

May 26, 2016 2:11 pm | by Duke Medicine News and Communications | Comments

Scientists have identified a molecular key that breast cancer cells use to invade bone marrow in mice, where they may be protected from chemotherapy or hormonal therapies that could otherwise eradicate them.


Stress Test Could Explain Male, Female Eating Disorders

May 26, 2016 1:51 pm | by Weizmann Institute of Science | Comments

A stress receptor in the brain is found to regulate metabolic responses to stressful situations differently in male and female mice.

Entire Brain’s Activity Captured in Just One Image

May 26, 2016 1:27 pm | by Rockefeller University | Comments

When it comes to measuring brain activity, scientists have tools that can take a precise look at a small slice of the brain (less than one cubic millimeter), or a blurred look at a larger area. Now, researchers describe a new technique that combines the best of both worlds — it captures a detailed snapshot of global activity in the mouse brain.


Here’s Why Fruit Flies Have Giant Sperm

May 26, 2016 1:22 pm | by University of Zurich | Comments

The fruit fly Drosophila bifurca is only a few millimeters in size but produces sperm that are almost six centimeters long. A team of researchers now provides the first conclusive explanation for the evolution of such giant sperm.

Dog Study Provides Answers About Brain Tumor Development

May 26, 2016 12:07 pm | by Elizabeth Doughman, Editor-in-Chief | Comments

Dogs are an excellent animal model for studying cancer, a recent study published in PLOS Genetics found. The research identified genes that could possibly play a role in the development of brain cancer in both dogs and humans.


USDA Issues Historic Fine Against Biotech Company in Animal Welfare Settlement

May 25, 2016 1:14 pm | by Lauren Scrudato, Associate Editor, Laboratory Equipment | Comments

Santa Cruz Biotechnology, Inc. has agreed to pay a $3.5 million fine, and revoke its research registration and dealer license in accordance with terms of a legal settlement with the U.S. Dept. of Agriculture.


Targeted Liver Cancer Treatment on the Horizon

May 25, 2016 1:10 pm | by University of Eastern Finland | Comments

A new molecular mechanism can be used to inhibit the growth of hepatocellular carcinoma, which is the most common liver cancer.


Teenage Brain Changes May Ease Traumatic Memories

May 25, 2016 12:57 pm | by Weill Cornell Medical College | Comments

Unique connections in the adolescent brain make it possible to easily diminish fear memories and avoid anxiety later in life. The findings may have important implications for the treatment of trauma and anxiety disorders.

An Easier Way to Study Blood Cancers

May 25, 2016 12:42 pm | by Christopher Vaughan, Stanford University | Comments

Researchers have developed a method of implanting cells to create a human bone-like structure in mice. This allows investigators to study a whole host of blood cancers and other diseases that they had trouble studying before.


Dog Study Identifies Genes Behind Three Rare Diseases

May 25, 2016 12:03 pm | by Elizabeth Doughman, Editor-in-Chief | Comments

Three canine genes for Caffey, Raine, and van den Ende-Gupta syndrome have been identified in a new study published in PLOS Genetics. These discoveries will help further the development of rare disease diagnostic and treatments, as well as veterinary diagnostics and breeding programs.


Exploring the Role of Transcription Factors in Lymphatic Diseases

May 24, 2016 1:27 pm | by Sarah Plumridge, Northwestern University Feinberg School of Medicine | Comments

In a recent study, scientists identified a pathway through which transcription factor proteins regulate lymphangiogenesis, the formation of lymphatic vessels from pre-existing lymphatic vessels. These results suggest a new mechanism for diseases associated with lymphatic vessels, which transport fluid out of tissues as part of the body’s lymphatic system.


Negative Enzyme Produces Positive Results

May 24, 2016 12:55 pm | by University of Geneva | Comments

Chemistry has provided many key tools and techniques to the biological community in the last twenty years. We can now make proteins that Mother Nature never thought of, image unique parts of live cells and even see cells in live animals.

Triple-Therapy Cocktail Combats Breast Tumors

May 24, 2016 12:49 pm | by Johns Hopkins Medicine | Comments

In a new study using mice and lab-grown human cells, a scientific team led by Johns Hopkins Kimmel Cancer Center researchers show how a triple-drug cocktail can shrink triple-negative breast cancers by killing off cancer cells and halting new tumor growth.



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