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The Lead

Fruit Flies Sleep Away Infection

April 22, 2014 | by Penn Medicine | Comments

When we get sick it feels natural to try to hasten our recovery by getting some extra shuteye. Researchers found that this response has a definite purpose, in fruitflies: enhancing immune system response and recovery to infection.     



Scientists Have Found a Potential Cure for Ebola

April 22, 2014 1:15 pm | by ScienceAlert | Comments

Working in a secretive quarantined lab, scientists in the US have discovered a small molecule that saves monkeys and rodents from one of the world's most terrifying viruses.                     


Are Lab Mice of Men?

April 21, 2014 1:26 pm | by Michael White, Pacific Standard | Comments

There have always been limitations to experiments done on mice, but new technology, which allows scientists to replace mouse genes with human genes, could clear the way for new ground to be broken.               


Source of Bladder Cancer Indentified in Mice

April 21, 2014 1:19 pm | by Stanford Medicine | Comments

A single type of cell in the lining of the bladder is responsible for most cases of invasive bladder cancer. A study, conducted in mice, is the first to pinpoint the normal cell type that can give rise to invasive bladder cancers.    


Link between Down Syndrome and Leukemia Found in Mice

April 21, 2014 1:03 pm | by Dana-Farber Cancer Institute | Comments

Although doctors have long known that people with Down syndrome have a heightened risk of developing acute lymphoblastic leukemia (ALL) during childhood, they haven’t been able to explain why. Now, investigators have uncovered a connection between the two conditions.


Alcohol Inhibits Muscle Repair in Rats

April 21, 2014 12:53 pm | by Thomas Jefferson Univ. | Comments

Muscle weakness is a common symptom of both long-time alcoholics and patients with mitochondrial disease. Now researchers have found a common link: mitochondria that are unable to self-repair.                 


Mouse Study Offers Clues to Improving Immunity in Premature Infants

April 21, 2014 12:36 pm | by Children's Hospital of Philadelphia | Comments

A new animal study by neonatology researchers at sheds light on immunology in newborns by revealing how gut microbes play a crucial role in fostering the rapid production of infection-fighting white blood cells, called granulocytes.     


Four TurnKey Conference Sessions Eligible for GBCI Credit

April 18, 2014 1:46 pm | Comments

Earn GBCI credit at the 2014 TurnKey Conference, held May 13-14 in National Harbor, MD by participating in one of the following sessions: Streamlining the Vivarium Facility Performance Verification Process, Are We There Yet? Bridging the Gap between Construction and Operation, Planning for the Unthinkable in Vivarium Design, and Facility Containment & Extreme Events: A Risk-Based Approach.


Boosting Depression in Mouse Brain Increases Resilience

April 18, 2014 1:24 pm | by Mount Sinai Health System | Comments

A new study points to a conceptually novel therapeutic strategy for treating depression. Instead of dampening neuron firing found with stress-induced depression, researchers demonstrated for the first time that further activating these neurons opens a new avenue to mimic and promote natural resilience.


Fruit Flies Replace Lost Stem Cells Naturally

April 18, 2014 1:08 pm | by Johns Hopkins Medicine | Comments

Researchers have discovered an unexpected phenomenon in the organs that produce sperm in fruit flies: When a certain kind of stem cell is killed off experimentally, another group of non-stem cells can come out of retirement to replace them.


How Zebrafish Maintain a Steady Gaze

April 18, 2014 12:56 pm | by Max Planck Institute | Comments

Scientists have discovered an array of new types of neurons, which help the brain of zebrafish to perceive, and compensate for, self-motion.                               


Innovative Strategy Facilitates Organ Repair

April 18, 2014 12:39 pm | by Inserm | Comments

A team of researchers has just demonstrated that the principle of adhesion by aqueous solutions of nanoparticles can be used in vivo to repair soft-tissue organs and tissues.                     


Jump-starting Natural Resilience Reverses Stress Susceptibility

April 17, 2014 3:41 pm | by NIH | Comments

Scientists have traced vulnerability to depression-like behaviors in mice to out-of-balance electrical activity inside neurons of the brain’s reward circuit and experimentally reversed it – but there’s a twist.           


Nasal Spray Could Protect against Any Flu

April 17, 2014 1:40 pm | by Univ. of St. Andrews | Comments

Scientists have developed a novel treatment that could protect against current, future and even pandemic strains of flu. The preventative treatment could be used as a "frontline defence" before an effective flu vaccine is developed.     


Essential Protein Needed for Fertilization

April 17, 2014 1:25 pm | by Wellcome Trust Sanger Institute | Comments

Researchers have discovered interacting proteins on the surface of the sperm and the egg essential to begin mammalian life. These proteins, which allow the sperm and egg to recognize one another, offer new paths towards improved fertility treatments and the development of new contraceptives.


Cancer Drugs Block Dementia-linked Brain Inflammation in Mice

April 17, 2014 1:11 pm | by Univ. of California, Irvine | Comments

A class of drugs developed to treat immune-related conditions and cancer — including one currently in clinical trials for glioblastoma and other tumors — eliminates neural inflammation associated with dementia-linked diseases and brain injuries.



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