A new male contraceptive could be on the horizon after scientists identified a novel way to block the transport of sperm during ejaculation. Scientists have found that complete male infertility could be achieved by blocking two proteins found on the smooth muscle cells that trigger the transport of sperm.
In a groundbreaking study, neuroscientists discovered that prenatal exposure to alcohol...
Scientists have identified an enzyme that can halt or possibly even reverse the build-up of...
A team of researchers has discovered that the protein PC7 plays a critical role in the brain by affecting certain types of cognitive performance such as anxiety, learning and emotional memory. Their results could have a significant impact on regulating behavior related to anxiety disorders and trauma.
A successful joint collaboration may lead to a potential treatment of brain diseases. The researchers found that a novel and unique compound selectively inhibits the process of aging in order to protect the brain from neurodegenerative diseases, without affecting lifespan. This is a first and important step towards the development of future drugs for the treatment of various neurodegenerative maladies.
A pharmacological inhibitor, ATN-224, induced cancer cell death and reduced tumor sizes in a mouse model of lung adenocarcinoma. ATN-224 dependent effects in animals were improved when the inhibitor was used in combination with another drug that activates programmed cell death.
Even if the obesity trend cannot be reversed, here's hope that it's partner in crime — diabetes — might be thwarted. Research shows how a recently discovered human peptide, called humanin, could lead to powerful new treatments for some people living with diabetes. In mice and rats, humanin analogue (a peptide molecularly similar to humanin) increases insulin secretion leading to an increase in glucose metabolism within beta cells.
Scientists have moved a step closer to an "obesity drug" that may block the effects of diets high in sugar and fats. In a new research report, scientists show that there is an abnormal amount of an inflammatory protein called PAR2 in the abdominal fat tissue of overweight and obese humans and rats.
Up until a few years ago, the common school of thought held that the mammalian heart had very little regenerative capacity. However, scientists now know that heart muscle cells constantly regenerate, albeit at a very low rate. Researchers have identified a stem cell population responsible for this regeneration.
President Barack Obama has signed a bill to support the retirement of federally owned chimpanzees once used for research by scientists at the National Institutes of Health (NIH) and elsewhere. According to The New York Times, the bill allows NIH to spend money once earmarked for research to support the move of nearly 300 federally owned chimps to a sanctuary in Keithville, La. NIH will keep 50 chimps for potential future research needs.
Trauma can scar people so indelibly that their children are affected. History provides examples of generations traumatized by war and starvation, whose children experience altered physiology. Now researchers have found an instance of animals passing on more specific information about a traumatic experience to their offspring. That information comes not through social communication, but through inheritance.
Bowing to scientists' near-universal scorn, the journal Food and Chemical Toxicology fulfilled its threat to retract a controversial paper claiming that a genetically modified (GM) maize causes serious disease in rats, after the authors refused to withdraw it.
Do fruit flies hold the key to treating dementia? Researchers have taken a significant step forward in unraveling the mechanisms of Pavlovian conditioning. Their work will help them understand how memories form and, ultimately, provide better treatments to improve memory in all ages.
Sex may in fact be one of the secrets to good health, youth and a longer life — at least for fruit flies. Male fruit flies that perceived sexual pheromones of their female counterparts — without the opportunity to mate — experienced more stress and rapid decreases in fat stores and resistance to starvation. The sexually frustrated flies lived shorter lives.
Scientists and surgeons have discovered a promising new approach to treating colorectal cancer by disarming the gene that drives self-renewal in stem cells that are the root cause of disease, resistance to treatment and relapse.
The United States may be losing ground as the leader in biomedical research and within the next five years will be second to China in the funds it spends for R&D, according to Francis Collins, director of the National Institutes of Health.
Blood stem cells that live in bone marrow split and divide down various pathways that ultimately produce red cells, white cells and platelets. These “daughter” cells must be produced at a rate of about one million per second to constantly replenish the body’s blood supply. Researchers have long wondered what allows these stem cells to persist for decades, when their progeny last for days, weeks or months before they need to be replaced.
Happy, sane males have better love lives — at least for mink. A first-ever study from the Univ. of Guelph reveals that relaxed, content male mink raised in enriched environments — cages complete with pools, toys and swings — are more successful in the mating season.