Tasting and spitting out toxic food is a survival trait shared by many complex organisms. Now researchers have shown that a simple roundworm, Caenorhabditis elegans, has the ability to spit out potentially deadly substances — a finding that could have surprising implications for human heart research.
Cancer can be caused solely by protein imbalances within cells, a study of ovarian cancer has...
Researchers have found from experiments in mice that the early flow of lymph fluid is a critical...
When does aging really begin? Two scientists now have a molecular clue. In a study of the...
Considering how many microorganisms we ingest each day, our gut has an extensive and well-developed immune system. This defense is involved in acute and chronic gut diseases, but it varies dramatically among people. A persistent question is how our genetic make-up affects our gut’s ability to fight infections.
In industrialized countries like Switzerland acute lymphoblastic leukemia represents the most frequent type of cancer in children. Together with international researchers, a pediatric oncologist from the University of Zurich has now succeeded in decoding a rare but always fatal subtype of this leukemia and in obtaining pointers for new therapeutic possibilities.
The functions of around 150 genes have been discovered by scientists across Europe in a major initiative to try to understand the part they play in disease and biology.
Scientists from the University of Southampton have developed a molecule that acts as an exercise mimic, which could potentially help treat type 2 diabetes and obesity.
A new drug that blocks cancer’s escape route from chemotherapy could be used to treat deadly lung and pancreatic cancers, new research reports.
The brain’s effect on other parts of the body has been well established. Now, a group of researchers has found that it’s a two-way street: Body fat can send a signal that affects the way the brain deals with stress and metabolism.
Investigators recently achieved great success with a study involving biomedical research on mouse models. The research group used tangible examples to demonstrate how the side effects of genetic modification of mice can complicate the interpretation of biomedical research.
Like a collection of ragtag villagers fighting off an invading army, the mix of bacteria that live in our guts may band together to keep dangerous infections from taking hold, new research suggests. But some “villages” may succeed better than others at holding off the invasion, because of key differences in the kinds of bacteria that make up their feisty population, researchers report.
If you find yourself downing that extra piece of chocolate fudge cake even though you're not hungry, it might be the absence of a hormone in your brain that's causing you to overeat purely for pleasure.
New research has found that when a gene is knocked out, other genes compensate for it's loss. The study in zebrafish, from Max-Planck-Gesellschaft, suggests caution when interpreting data from molecular biological studies or developing gene therapy to treat various diseases.
Calming a neural circuit in the brain can alleviate stress in mice, according to new research that could lay the foundation for understanding stress and anxiety in people.
Although the causes of many age-related diseases remain unknown, oxidative stress is thought to be the main culprit. Oxidative stress has been linked to cardiovascular and neurodegenerative diseases including diabetes, hypertension and age-related cancers. However, researchers at the University of Missouri recently found that aging actually offered significant protection against oxidative stress.
A new study from The University of Texas Medical Branch at Galveston has uncovered a mechanism that is central to becoming allergic to ragweed pollen and developing allergic asthma or seasonal nasal allergies. The findings are currently available online in the American Journal of Respiratory Cell and Molecular Biology.
For decades, the public has been told to avoid foods high in saturated fats and cholesterol. A new study led by the National Marine Mammal Foundation (NMMF) and published in PLOS ONE discovered a saturated fat, called heptadecanoic acid, that may help reverse prediabetes in humans.
Using large-scale zebrafish drug-screening models, researchers at Boston Children's Hospital have identified a potent group of chemicals that helps bone marrow transplants engraft or "take." The findings, published in the July 23 issue of Nature, could lead to human trials in patients with cancer and blood disorders within a year or two, says senior investigator Leonard Zon, MD.