Subscribe to Controlled Environments

The Lead

Exercise Protects Against Neurodegenerative Disease in Mice

November 24, 2015 | by Elizabeth Doughman, Editor-in-Chief | Comments

Exercise increases levels of a brain-protecting enzyme in mice, according to a new study from Johns Hopkins University. This finding could have implications for people with a variety of neurodegenerative diseases, such as Alzheimer's, Parkinson's, Huntington's, and epilepsy.


Hydra Give Clues to Human Regeneration

November 24, 2015 12:00 am | Comments

Champion of regeneration, the freshwater polyp Hydra is capable of reforming a complete individual from any fragment of its body. It is even able to remain alive when all its neurons have disappeared. Researchers have discovered how: cells of the epithelial type modify their genetic program by overexpressing a series of genes, among which some are involved in diverse nervous functions.


How Fast You Move Can Predict How Healthy You'll Be

November 23, 2015 9:48 am | Comments

As humans have begun to live longer it has become clear that the quality of our lives is equally as important as the duration. 


How Weight-loss Surgery Reduces Sugar Cravings

November 23, 2015 9:17 am | Comments

A new study found that gastrointestinal bypass surgery, which is used to treat morbid obesity and diabetes, reduced sugar-seeking behavior in mice by reducing the release of a reward chemical called dopamine in the brain. The findings suggest that positive outcomes are more likely if sugary foods seem less rewarding after surgery.


Researchers Develop Model to Study, Find Ways to Target Rare Tumor

November 23, 2015 9:17 am | Comments

Cancer researchers at the University of Cincinnati have found a new target that could lead to therapies for a rare type of tumor.


Running Prevents Postnatal Side Effects of Epilepsy Drugs in Mice

November 23, 2015 9:16 am | Comments

The simple act of running may be sufficient to prevent long-term cognitive impairments caused by prenatal exposure to antiepileptic drugs, according to a study published November 19th in Stem Cell Reports.


A Newly Discovered Signaling Molecule Helps Neurons Find Their Way in the Developing Brain

November 23, 2015 9:16 am | Comments

During embryonic development, billions of neurons nimbly reposition themselves within the brain and spinal cord, and connect branches to form the neural circuits that ultimately control our movements, perception, and memory. Scientists have long sought to understand the driving forces in this meticulously choreographed dance.


A New Way to Monitor Vital Signs

November 20, 2015 9:26 am | by Anne Trafton, MIT | Comments

Using technology invented at MIT, doctors may one day be able to monitor patients’ vital signs by having them swallow an ingestible electronic device that measures heart rate and breathing rate from within the gastrointestinal tract.

New Strategy Reduces Side Effects in Parkinson's Treatment

November 20, 2015 9:25 am | Comments

Northwestern Medicine scientists and international colleagues have identified a novel strategy for reducing the side effects of uncontrolled movement caused by the drug levodopa, commonly used to treat the stiffness, tremors and poor muscle control of Parkinson’s disease.


Study in Mice Suggests Coconut Oil Can Control Overgrowth of a Fungal Pathogen in GI Tract

November 20, 2015 9:24 am | Comments

A new inter-disciplinary study led by researchers at Tufts University found that coconut oil effectively controlled the overgrowth of a fungal pathogen called Candida albicans in mice. In humans, high levels of C. albicans in the gastrointestinal tract can lead to bloodstream infections, including invasive candidiasis.


NIH to Release Last Remaining Research Chimps Into Retirement

November 19, 2015 1:46 pm | by Seth Augenstein, Digital Reporter | Comments

The final 50 chimpanzees held for research purposes in the U.S. are being released – a development cheered by animal-rights groups, but bemoaned by advocates of animal research.


Scientists Grow Functional Vocal Cord Tissue in the Lab

November 19, 2015 10:31 am | Comments

University of Wisconsin scientists have succeeded in growing functional vocal-cord tissue in the laboratory, a major step toward restoring a voice to people who have lost their vocal cords to cancer surgery or other injuries.


Mathematical Model Helps Show How Zebrafish Get Their Stripes

November 19, 2015 9:21 am | Comments

A mathematical model developed by Brown University researchers is shedding new light on how zebrafish get their iconic stripes. The model helps to demonstrate how two dynamic processes—the movement of pigment cells across the skin, and the birth and death of cells as the fish grows—combine to keep zebrafish stripes in line.


Obesity and Type 2 Diabetes Harm Bone Health

November 19, 2015 9:20 am | Comments

In a new animal study, researchers found obesity and Type 2 diabetes negatively affected bone, but exercise prevented weight gain and diabetes and increased bone strength. These findings could inform interventions to improve bone health among individuals with obesity and Type 2 diabetes.


Heart Drug Protects Fertility in Chemo-treated Female Mice

November 19, 2015 9:20 am | by Elizabeth Doughman, Editor-in-Chief | Comments

A heart medication prevented ovarian damage and improved survival in adolescent mice after chemotherapy, according to a new study from the University of Wisconsin-Madison. The drug, dexrazoxane (or dexra for short), could save lives as well as overcome limitations of current fertility treatments used during cancer treatment.


Researchers Identify Emergency Response System for Blood Formation

November 18, 2015 9:23 am | Comments

Scientists at the Children’s Medical Center Research Institute at UT Southwestern have determined how the body responds during times of emergency when it needs more blood cells.



You may login with either your assigned username or your e-mail address.
The password field is case sensitive.