Researchers have discovered interacting proteins on the surface of the sperm and the egg essential to begin mammalian life. These proteins, which allow the sperm and egg to recognize one another, offer new paths towards improved fertility treatments and the development of new contraceptives.
Scientists have developed a novel treatment that could protect against current, future and even...
The major goal of a bio-containment operation is to maintain the primary and secondary facility...
The University of Louisville's health sciences campus has thousands of rats and mice — and...
A class of drugs developed to treat immune-related conditions and cancer — including one currently in clinical trials for glioblastoma and other tumors — eliminates neural inflammation associated with dementia-linked diseases and brain injuries.
Researchers have developed a mutated mouse model that mimics the human mutation of an eye mobility disorder in order to understand why it occurs.
In a feat of reverse tissue engineering, researchers have begun to unravel the complex genetic coding that allows embryonic cells to proliferate and transform into all of the specialized cells that perform a myriad of different biological tasks.
A team researchers show in a study of rhesus monkeys that hair can reveal the womb environment in which an infant formed.
Over 20 years after the fatal fialuridine trial, a study demonstrates that mice with humanized livers recapitulate the drug's toxicity.
Nematode worms, fruit flies, mice and other lab animals live longer, healthier lives when they eat less than they otherwise would if more food were available. Researchers have declared the most popular theory doesn’t make evolutionary sense, and they’ve proposed a new explanation in its place.
Scientists report that they’ve developed a simple, “3D” laboratory method to test asthma and allergy medications that mimics what happens in the body, which could help reduce the need for animal testing.
Tissue engineering has been used to construct natural esophagi, which in combination with bone marrow stem cells have been safely and effectively transplanted in rats.
Limiting a certain protein in the brain reverses Alzheimer’s symptoms in mice. Researchers found that the overproduction of the protein known as p25 may be the culprit behind the sticky protein-fragment clusters that build up in the brains of Alzheimer's patients.
A team of scientists have published details of how a class of drugs called “HDACis” drive muscle-cell regeneration in the early stages of dystrophic muscles, but fail to work in late stages.
By tracking brain activity when an animal stops to look around its environment, neuroscientists believe they can mark the birth of a memory.
One lucky attendee at this year’s TurnKey Conference will receive a $1,000 travel voucher to TurnKey 2015 to be held in San Diego! The drawing will be held and the winner announced during the 2014 Conference, held May 13-14 at the Gaylord National Hotel in MD. Winner must be present to win.
It is with great sorrow that ALN marks the passing of Ken Macleod. Ken leaves to mourn his wife Meg and their children. He will be sadly missed but never forgotten by his many friends and business associates.
Ketamine, an anesthetic sometimes abused as a street drug, increases the synaptic connections between brain cells and in low doses acts as a powerful antidepressant. However, stress has the opposite effect, shrinking the number of synaptic spines, triggering depression.
Mice engineered to express Lin28 in their kidneys developed Wilms tumor, which regressed when Lin28 was withdrawn, indicating that strategies aimed at blocking or deactivating the gene hold therapeutic promise for children with Wilms.