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Long-term Space Effects Produce Cognitive Impairment in Rats

April 24, 2014 | by Johns Hopkins Medicine | Comments

Scientists report that rats exposed to high-energy particles, simulating conditions astronauts would face on a long-term deep space mission, show lapses in attention and slower reaction times, even when the radiation exposure is in extremely low dose ranges.

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Brain Circuit Drives Rest and Activity in Fruit Flies

April 24, 2014 2:39 pm | by Penn Medicine | Comments

A study describes a circuit in the brain of fruit flies that controls their daily, rhythmic behavior of rest and activity. It also found that the fly version of a human brain protein is a major coordinating molecule in this circuit.     

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TurnKey Session of the Week: NIH to Present Changes to Manual

April 24, 2014 8:23 am | Comments

The National Institutes of Health (NIH) Design Requirements Manual (DRM) is the only comprehensive design requirements and guidance manual for biomedical research laboratory and animal research facilities in the U.S. Compliance with the DRM ensures that NIH owned, leased and funded facilities will be of the highest quality and provides the minimum standards for other institutions around the world.

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Gene Therapy May Boost Cochlear Implants

April 23, 2014 5:01 pm | by Lauran Neergaard, Associated Press | Comments

Australian researchers are trying a novel way to boost the power of cochlear implants: They used the technology to beam gene therapy into the ears of deaf animals and found the combination improved hearing.            

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Protein Expression Gets Mouse Heart Pumping

April 23, 2014 1:14 pm | by Baylor College of Medicine | Comments

Most people think the development of the heart only happens in the womb, however the days and weeks following birth are full of cellular changes that play a role in the structure and function of the heart.             

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Two Genes Linked to Inflammatory Bowel Disease

April 23, 2014 12:34 pm | by Univ. of Cincinnati Academic Health Center | Comments

Researchers have done what is believed to be the first direct genetic study to document the important function for the Ron receptor, a cell surface protein often found in certain cancers, and its genetic growth factor, responsible for stimulating cell growth, in the development and progression of IBD.

Pain Curbs Sex Drive in Female Mice, but Not in Males

April 23, 2014 12:28 pm | by McGill Univ. | Comments

Researchers have investigated, possibly for the first time in any species, the direct impact of pain on sexual behavior in mice.                                   

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Male Health Linked to Testosterone in Womb

April 23, 2014 12:17 pm | by Univ. of Edinburgh | Comments

Men's susceptibility to serious health conditions may be influenced by low exposure to testosterone in the womb, new research suggests.                                 

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Relieving Pain in Mice without Hurting the Heart

April 22, 2014 1:48 pm | by Penn Medicine | Comments

Nonsteroidal antinflamatory drugs (NSAIDs) that block an enzyme called COX-2 relieve pain and inflammation but can cause heart attacks, stroke, heart failure, and even sudden cardiac death. This has prompted a decade-plus search for safer, but still effective, alternatives to these commonly prescribed, pain-relieving drugs.

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Fat Metabolism Altered in Animals Prevents Heart Disease

April 22, 2014 1:32 pm | by Johns Hopkins Medicine | Comments

Working with mice and rabbits, Johns Hopkins scientists have found a way to block abnormal cholesterol production, transport and breakdown, successfully preventing the development of atherosclerosis.               

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Scientists Have Found a Potential Cure for Ebola

April 22, 2014 1:15 pm | by ScienceAlert | Comments

Working in a secretive quarantined lab, scientists in the US have discovered a small molecule that saves monkeys and rodents from one of the world's most terrifying viruses.                     

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Mouse Model Links Diatary Fats, Colon Cancer Tumor Growth

April 22, 2014 1:09 pm | by Arizona State Univ. | Comments

Scientists have shown new genetic evidence that could strengthen the link between the role of dietary fats and colon cancer progression.                                 

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Fruit Flies Sleep Away Infection

April 22, 2014 12:58 pm | by Penn Medicine | Comments

When we get sick it feels natural to try to hasten our recovery by getting some extra shuteye. Researchers found that this response has a definite purpose, in fruitflies: enhancing immune system response and recovery to infection.     

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Are Lab Mice of Men?

April 21, 2014 1:26 pm | by Michael White, Pacific Standard | Comments

There have always been limitations to experiments done on mice, but new technology, which allows scientists to replace mouse genes with human genes, could clear the way for new ground to be broken.               

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Source of Bladder Cancer Indentified in Mice

April 21, 2014 1:19 pm | by Stanford Medicine | Comments

A single type of cell in the lining of the bladder is responsible for most cases of invasive bladder cancer. A study, conducted in mice, is the first to pinpoint the normal cell type that can give rise to invasive bladder cancers.    

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Link between Down Syndrome and Leukemia Found in Mice

April 21, 2014 1:03 pm | by Dana-Farber Cancer Institute | Comments

Although doctors have long known that people with Down syndrome have a heightened risk of developing acute lymphoblastic leukemia (ALL) during childhood, they haven’t been able to explain why. Now, investigators have uncovered a connection between the two conditions.

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