The standard of care for adult patients with glioblastoma includes surgical resection, radiotherapy and chemotherapy, but even with those aggressive treatments median survival is only just over a year. The goal of the researchers is to understand how manipulating immunosuppressive pathways can increase survival when combined with existing therapies.
After adolescent rodents were exposed to THC, researchers noted substantial and persistent...
Previous studies have shown an association between high folic acid intake and a reduction in the...
Researchers show that stroke conditions may increase brain plasticity and recovery in some cases...
Some of the earliest nerve cells to develop in the womb shape brain circuits that process sights and sounds, but then give way to mature networks that convert this sensory information into thoughts.
Depression is a serious issue for expecting mothers. Left untreated, depression could have implications for a fetus's health. But treating the disease during pregnancy may carry health risks for the developing fetus, which makes an expecting mother's decision whether to take medication a very difficult one.
In real estate, location is key. It now seems the same concept holds true when it comes to stopping pain.
Duke University researchers have discovered a promising target for renal cell carcinomas. A study appearing online Feb. 1, 2016 in Cancer Research shows that the majority of these cancers rewire their metabolism in a way that leaves them addicted to an outside nutrient called cystine.
A team of researchers discovered that a pro-inflammatory signaling protein, or cytokine, called IL-33, plays a key role in recruiting phagocytes to damaged retina and inducing retinal degeneration.
As brain cells age they lose the fibers that receive neural impulses, a change that may underlie cognitive decline. Researchers at the University of California, Irvine recently found a way to reverse this process in rats.
It is normal for our immune system to occasionally fly into an inflammatory rage to defend the host (us) against pathogens or even tumor cells. Problems arise when the rage persists or is re-directed against one’s self, as occurs in autoimmune disease.
New research suggests that ravens share at least some of the human ability to think abstractly about other minds, adapting their behavior by attributing their own perceptions to others.
Two proteins, p38 gamma and p38 delta, control the accumulation of fat in the liver, a process linked to the development of insulin resistance and diabetes, which are common outcomes of obesity. The study shows that inhibition of these proteins with specific inhibitors has potential as a treatment for fatty liver disease.
A new mouse-human modeling system could be used to study neural crest development as well as the modeling of a variety of diseases, according to a new study from the Whitehead Institute.
University of Massachusetts Medical School researchers have found a way to more efficiently delivery a CRISPR/Cas9 therapeutic to adult mice with the metabolic disease Tyrosinemia type I that may also prove to be safer for use in humans.
Scientists at EPFL have solved a longstanding problem with modeling Parkinson’s disease in animals. Using newfound insights, they have improved both cell and animal models for the disease, which can propel research and drug development.
There’s apparently safety in numbers, even for cancer cells. New research in mice suggests that cancer cells rarely form metastatic tumors on their own, preferring to travel in groups since collaboration seems to increase their collective chances of survival, according to researchers at Johns Hopkins.
In the face of a disrupted circadian rhythm, a low-salt diet and a hormone known to constrict blood vessels have the same unhealthy result: elevated resting blood pressure and vascular disease, scientists report.
Male mice without any Y chromosome genes can father offspring with assisted reproduction, according to a new study from the University of Hawaii at Monoa. This finding furthers understanding of the Y chromosome gene function and evolution.