BSL-3

Waste Matters

The next series of articles in this column will deal with processing waste materials in BSL-3 containment.


The Containment Barrier – Testing It Right, Part 2

Let’s move onto a discussion of recording test data, defining integrity testing, and some thoughts on developing a test standard using approaches developed in Australia and New Zealand.


The Containment Barrier - Testing It Right, Part 1

How do we manage these risks effectively? As with most things, early prevention is the best cure.


Containment Barrier Function and Performance

When you think about BSL-3 and higher biocontainment laboratories, working with dangerous pathogens in cabinets or with infected animals, it is understood that, “these are no ordinary laboratories.”


Meeting the BMBL Requirement of No Airflow Reversal from ABSL-3 and BSL-3 Rooms

One of the most challenging issues for today’s BSL-3 facilities is the BMBL statement, “The laboratory shall be designed such that under failure conditions the airflow will not be reversed.”


Pressure, Volume, and Directional Airflow Objectives

The purpose of directional airflow is the protection of people and the environment where there has been an airborne release of an infectious agent.


Simple Airflow Strategies Provide You the Greatest Reliability

How do we best meet the BMBL 5th Edition requirement which states that, “the laboratory shall be designed such that under failure conditions the airflow will not be reversed?”


The BMBL 5th Edition: A Model of Continuity and Change

BMBL is in principle the basis of design for every biocontainment facility in the U.S. and for many other parts of the world.


A Commitment to Containment

As long as we underpin the solutions we discuss with the containment principles they illustrate, you can use the information to help determine what the right options may be for your facility and organization.


The Latest Buzz on Insectaries

In the last ten years, there has been a considerable increase in demand for insectaries in laboratories, particularly in the government sector. This article will explore the reasons behind the increase in demand, the guidelines used to design these facilities, and the common characteristics and details of design.

Thoughts on the Visibility of Containment (and how we can learn from it)

The first point I would like to make is that incidents related to containment facilities make a good story in the eyes of the press.


Chemical Treatment System for Liquid Effluent

A waste treatment system was designed and built to process liquid effluent from a laboratory/vivarium working with human pathogenic viruses based on de-activation by exposure to aqueous solutions of sodium hypochlorite.


Perspectives in Alkaline Hydrolysis

The commercialization of alkaline hydrolysis technology used in tissue digester systems has led to many new innovations in the process and equipment design — some of which have led consumers to many perceptions and misconceptions regarding the process.


The Greening of Containment

We must challenge the existing paradigms in both operation and design if we are to make significant impact on sustainability in laboratories.


Laboratory Design to Support Marine Animals

Designing science laboratories that support healthy marine animals requires environmental alignment with dynamic seawater coastlines, presenting numerous issues for architects and engineers.


New Fire Protection Code Will Impact Animal Facilities

Implementation of NFPA 150 in its current form will have widespread space planning impacts, cost implications, and could functionally prohibit the use of common protocols and equipment within laboratory related Animal Housing Facilities.


More on Biocontainment Security

In dealing with the design and operations of facilities that handle hazardous biological organisms, consistent and objective guidance, rules, and regulations are critical.


Security and Risk

Biosafety and biocontainment considerations have historically been based on risk assessment. Risk assessment in biocontainment has had a subjective component that makes it difficult to measure.


Isolation Technology as Applied to Lab Animal Research

Cost and process improvement within biocontainment space


Certification and Risk

In this series of columns on certification, we started out discussing certification from the perspective of objective standards.


Certification of Containment Equipment and Facilities

Certification — confirmation that some fact or statement is true through the use of documentary evidence.


Additional Thoughts on Directional Airflow

A look at the benefits and limitations of directional air inflow


Implementing a Medical Surveillance Program for Animal Care Staff

Medical surveillance programs protect both employees and institutions.


Old Dog, New Tricks

How 50-year-old Cubicles are Changing with the Times


Facility Integration of a BSL-3Ag Facility

Successful facility integration is best accomplished by bringing together an integrated team with project roles in planning, facility design, equipment selection and integration, construction, and commissioning, providing the resources for complete project responsibility.