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Withrow & MacEwen's Small Animal Clinical Oncology, Fourth Edition was published in 2007 by Saunders, an imprint of Elsevier Inc. The authors, Stephen J. Withrow and David M. Vail, collaborated with over 25 contributors in the field of oncology to revise this latest edition. Previous editions were published in 1989, 1996, and 2001. Oncology is an ever evolving discipline which has and continues to make strides in understanding the biology, diagnostic capabilities, treatment therapies, and prognoses of cancer. This text is written to provide the most current and relevant information for small animal veterinarians, veterinary students, as well as animal care technicians interested in the study of clinical oncology.
The text is divided into four sections: The Biology and Pathogenesis of Cancer, Diagnostic Procedures for the Cancer Patient, Therapeutic Modalities for the Cancer Patient, and Specific Malignancies in the Small Animal Patient. The sections are further divided into specific chapters, complete with page indicators and extensive reference lists for ease of locating information. An excellent brief introduction written by Withrow explains why veterinarians and researchers should be concerned about cancer in small animals. From its rise in prevalence to the comparative studies between humans and small animals, much information can be learned and extrapolated between the similar cancer groups, assisting both humans and animals with better understanding and treatment of cancer in general.
The fundamental principles of tumor biology and the latest diagnostic procedures are discussed thoroughly and include clear line diagrams, radiograph images, and excellent color photomicrographs of cytologic specimens. Chapter 14: Molecular/Targeted Therapy of Cancer is not a subject that most veterinarians have experience with, so the relevant information in this chapter will allow practitioners to make better informed decisions regarding referral to oncology centers, keep abreast of promising novel gene therapy for cancer, and current limitations with molecular and genetic technologies. Supportive care for the patient and their human families is explored in subsequent chapters, paying a significant amount of attention to the comfort of the pet and the family's ability to assist in their pet's care both physically and emotionally. Complementary and alternative medicines are likewise addressed.
Part IV: Specific Malignancies in the Small Animal Patient is a systems approach to oncology with each chapter representing a body system and its typical cancer representation. It follows similar format from system to system: incidence, risk factors, history, clinical signs, diagnostic techniques, treatment, and prognosis are all discussed. Excellent flowcharts, photographs, and tables enhance the understanding and interest in all of the final chapters. References are included all chapters with some suggested reading when applicable.
The authors have done a tremendous job addressing the multitudinous facets of small animal oncology. The organization and content of the text lends itself well to the usefulness for the general practitioner, veterinary student, and animal care technician. The text is interesting and easy to read, locating specific topics quickly and easily. Developments in technology such as the identification of the canine genome, molecular abnormalities in cancer pathways, and collaboration of the medical and research communities through the Comparative Oncology Program at the National Cancer Institute have lead to measured successes in various cancer diagnoses and treatments. The authors have updated this edition to reflect advancements in medicine now and what may develop in the future.
Sandra L. Jex is a veterinarian and consultant. She can be reached at editors@alnmag.com.