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The Lead

A Sugary Diet During Pregnancy Leads to Obese Offspring

February 11, 2016 | by Elizabeth Doughman, Editor-in-Chief | News | Comments

Pregnant mice that received a high fructose diet was more likely to give birth to offspring that were hypertensive, insulin resistant, and obese, according to a study presented at the Society for Maternal-Fetal Medicine's annual meeting.

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New NIH Policy Requires Researchers to Evaluate 'Sex as a Biological Variable'

February 12, 2016 10:55 am | by Lauren Scrudato, Associate Editor, Laboratory Equipment | News | Comments

As more drugs hit the market, instances of women having complications from tested and approved drugs prompted the National Institutes of Health and Congress to require that women be included in research involving human subjects, officially named the Revitalization Act.

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Blocking Stress Protein Relieves Chronic Pain in Mice

February 12, 2016 9:42 am | News | Comments

A group of drugs being developed to treat mood disorders could also relieve chronic pain, finds new UCL (University College London) research funded by the Medical Research Council.

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Vinegar Could Potentially Help Treat Ulcerative Colitis

February 12, 2016 9:41 am | News | Comments

Vinegar is the perfect ingredient for making tangy sauces and dressings. Now, researchers report in ACS' Journal of Agricultural and Food Chemistry that the popular liquid could also help fight ulcerative colitis, an inflammatory bowel disease that research suggests is related to the gut microbiome.

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Pump Rental Service

February 11, 2016 5:15 pm | by SAI - Infusion Technologies | SAI - Infusion Technologies | Product Releases | Comments

Infusion pumps are usually the most expensive component of infusion systems. Whether confronting a study with a large number of animals, or running your first infusion study, it is not always possible or cost effective to purchase new pumps. In these situations the best option may be to rent the pumps you need for the duration of the infusion.

Pain Management Tips and Tricks

February 11, 2016 4:38 pm | by Mary Ellen Goldberg BS, LVT, CVT, SRA, CCRA | Articles | Comments

Pain has been called the “fourth vital sign” after body temperature, heart rate, and respiratory rate, and its potential presence should be evaluated in patients just as other vital signs. It motivates us to withdraw from potentially damaging situations, protect a damaged body part while it heals, and avoid those situations in the future.

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Smart Pass-Through™ with Recirculating HEPA Filtration

February 11, 2016 3:33 pm | by Terra Universal, Inc. | Terra Universal, Inc. | Product Releases | Comments

Smart Pass-Through™ with Recirculating HEPA Filtration from Terra Universal Fullerton, CA – Pass-through chambers save time and money by allowing clean transfer of materials between rooms of different cleanliness ratings; personnel can avoid the gowning process.

Ambulatory Infusion System

February 11, 2016 11:49 am | by Lomir Biomedical, Inc. | Lomir Biomedical, Inc. | Product Releases | Comments

Preclinical continuous infusion in large laboratory animals increasingly is accomplished using ambulatory (non-tethered) models. In such models, the animals freely move about the cage or pen without a tether constraint. Ambulatory infusion comprises a jacket, a small, portable pump, and an implanted port or catheter.

Researchers Resolve Longstanding Issue of Components Needed to Regenerate Muscle

February 11, 2016 9:32 am | by Susan Gammon, Ph.D., Sanford-Burnham Prebys Medical Discover Unit | News | Comments

Researchers have conclusively identified the protein complex that controls the genes needed to repair skeletal muscle. The discovery clears up deep-rooted conflicting data and will now help streamline efforts towards boosting stem cell-mediated muscle regeneration.

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Study Shows Promising Safety Results for Anti-aging Drug

February 11, 2016 9:32 am | News | Comments

Previous studies on the metabolic side effects of rapamycin have made it unclear whether the drug is safe as a long-term treatment. A recent study showed minimal metabolic side effects after continuous, long-term treatment with encapsulated rapamycin in a marmoset (monkey) model.

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Starfish Reveal the Origins of Brain Messenger Molecules

February 11, 2016 9:32 am | News | Comments

Publishing in the Royal Society journal Open Biology, the team led by Professor Maurice Elphick at QMUL’s School of Biological and Chemical Sciences report 40 new neuropeptide genes discovered for the first time in the common European starfish Asterias rubens.

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Extremophile Fish's Adaptation to Pollution May Lead to Biomedical Applications

February 11, 2016 9:31 am | by Eric Sorensen, Washington State University | News | Comments

A Washington State University biologist has found the genetic mechanism that lets a fish live in toxic, acidic water. The discovery opens new insights into the functioning of other “extremophiles” and how they adapt to their challenging environments.

Eggs May Help Diabetics with a Vitamin D Deficiency

February 11, 2016 9:31 am | News | Comments

A simple change in diet could boost vitamin D levels for millions of Americans suffering from Type 2 diabetes, according to new research from Iowa State University published in the Journal of Agricultural and Food Chemistry.

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Professional Profile: Ken Henderson, Ph.D, MS

February 10, 2016 5:24 pm | by Elizabeth Doughman, Editor-in-Chief | Articles | Comments

ALN spoke with Ken Henderson, Ph.D., MS, the Senior Director of Laboratory Services at Charles River supporting Global Infectious Disease and Genetic Diagnostics. Ken is a member of the distinguished facilty speaking at the 2016 TurnKey Conference, which will be held May 24-25 in Oxon City, MD (Washington DC).

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Gut Environment Could Reduce Severity of Malaria

February 10, 2016 10:19 am | News | Comments

Microorganisms in the gut could play a role in reducing the severity of malaria, according to a new study co-authored by UT researchers.

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Aerobic Exercise Helps Rats Learn

February 10, 2016 10:12 am | News | Comments

It may be possible to increase the neuron reserve of the hippocampus – and thus improve preconditions for learning – by promoting neurogenesis via sustained aerobic exercise such as running.

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