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Commissioning Verification and Validation

July 23, 2014 | by Gilles Tremblay and Spencer Andrews | Articles | Comments

One of the most critical challenges facing today’s research facilities is the acquisition of regulatory compliance—that stamp of approval that defines an institution as highly qualified, safe and desirable for the demands and challenges of complex and highly technical research.

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Cardiovascular researchers at have successfully used a protein known as MG53 to treat acute and chronic lung cell injury. Additionally, application of this protein proved to prevent lung cell injury.

Protein Therapy Successful Treats Injured Lung Cells in Animal Model

July 24, 2014 2:18 pm | by Ohio State Univ. | News | Comments

Cardiovascular researchers have successfully used a protein known as MG53 to treat acute and chronic lung cell injury. Additionally, application of this protein proved to prevent lung cell injury.               

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Cancer Drug Given Orally to Mice Improves Alzheimer's

July 24, 2014 1:36 pm | by American Chemical Society | News | Comments

Currently, no cure exists for Alzheimer’s disease. But scientists are now reporting new progress on a set of compounds, initially developed for cancer treatment, that shows promise as a potential oral therapy for Alzheimer’s.       

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Self-contained Water Treatment and Delivery

July 24, 2014 8:21 am | Systems Engineering | Product Releases | Comments

The ReCIRC POD™, a modular self-contained water treatment and delivery system, features a 5.0 micron pre-filter, integrated RO unit, stainless steel re-circulating tank, UV sterilizing unit, and pump.

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A study reveals a novel pathway in the pathophysiology of epilepsy.   Researchers have identified the basic cellular mechanism that goes awry in prickle mutant flies, leading to the epilepsy-like seizures.

Genetic Link between Epilepsy and Neurodegenerative Disorders Seen in Mutant Flies

July 23, 2014 2:22 pm | by John Riehl, Univ. of Iowa | News | Comments

A study reveals a novel pathway in the pathophysiology of epilepsy. Researchers have identified the basic cellular mechanism that goes awry in prickle mutant flies, leading to the epilepsy-like seizures.             

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The use of a virus designed to target and kill cancer cells alongside isolated limb perfusion chemotherapy — given directly to blood vessels supplying the affected arm or leg as an alternative to amputation — was more effective in rats than either treatme

Viral Therapy Boosts Limb-saving Cancer Treatment in Rats

July 23, 2014 2:03 pm | by The Institute of Cancer Research | News | Comments

The use of a virus designed to target and kill cancer cells alongside isolated limb perfusion chemotherapy — given directly to blood vessels supplying the affected arm or leg as an alternative to amputation — was more effective in rats than either treatment on its own.

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Researchers have developed a vaccine that can combat dust-mite allergies by naturally switching the body’s immune response.

Vaccine Reduces Dust-mite Allergies in Lab Animals

July 23, 2014 1:42 pm | by Richard Lewis, Univ. of Iowa | News | Comments

Researchers have developed a vaccine that can combat dust-mite allergies by naturally switching the body’s immune response. In animal tests, the nano-sized vaccine package lowered lung inflammation by 83 percent despite repeated exposure to the allergens.

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Bacteria that produce a therapeutic compound in the gut inhibit weight gain, insulin resistance and other adverse effects of a high-fat diet in mice, Vanderbilt University investigators have discovered.

Therapeutic Bacteria Prevents Obesity in Mice

July 23, 2014 1:31 pm | by Vanderbilt Univ. | News | Comments

Bacteria that produce a therapeutic compound in the gut inhibit weight gain, insulin resistance and other adverse effects of a high-fat diet in mice, investigators have discovered.                   

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Pre-filled Water Bottles

July 23, 2014 8:27 am | Innovive, Inc. | Product Releases | Comments

Aquavive® Pre-Filled Water Bottles for mouse and rat eliminate washing and processing steps from vivarium operations.

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A team of scientists has identified a key regulator of developmental timing. The researchers describe how LIN-42, a gene that is found in animals across the evolutionary tree, governs a broad range of events throughout development.

Gene Found in Worms Controls Timing of Events during Maturation

July 22, 2014 2:45 pm | by Cold Spring Harbor Laboratory | News | Comments

A team of scientists has identified a key regulator of developmental timing. The researchers describe how LIN-42, a gene that is found in animals across the evolutionary tree, governs a broad range of events throughout development.     

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Cold-blooded animals cannot regulate their body temperature, so their cells are stressed when facing temperature extremes. Worse still, even at slightly colder temperatures, some biological processes in the cell are slowed down more than others, which sho

Process Helps Fruit Flies Cope with the Cold

July 22, 2014 2:25 pm | by Univ. of Rochester | News | Comments

Cold-blooded animals cannot regulate their body temperature, so their cells are stressed when facing temperature extremes. Worse still, even at slightly colder temperatures, some biological processes in the cell are slowed down more than others, which should throw the cells’ delicate chemical balance out of whack. Yet, those cells manage to keep their biological processes coordinated. Now, researchers have found out how they do that.

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Scientists have generally believed that HIV and its monkey equivalent, SIV, gain a permanent foothold in the body very early after infection, making it difficult to completely eliminate the virus even after antiretroviral therapy has controlled it. Now re

NIH-supported Scientists Demonstrate Very Early Formation of SIV Reservoir

July 22, 2014 2:17 pm | by NIH | News | Comments

cientists have generally believed that HIV and its monkey equivalent, SIV, gain a permanent foothold in the body very early after infection, making it difficult to completely eliminate the virus even after antiretroviral therapy has controlled it. Now researchers report that SIV can become entrenched in tissues fewer than 3 days after infection, before the virus is detectable in blood plasma (the liquid part) or blood cells.

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A new study in mice reveals that mesenchymal (mezz-EN-chem-uhl) stem cells (MSCs) help rejuvenate skeletal muscle after resistance exercise.

Stem Cells Help Mice Bulk Up

July 22, 2014 2:10 pm | by Diana Yates, Univ. of Illinois at Urbana-Champaign | News | Comments

A new study in mice reveals that mesenchymal (mezz-EN-chem-uhl) stem cells (MSCs) help rejuvenate skeletal muscle after resistance exercise. Researchers were able to increase the rate of repair and enhance the growth and strength of muscles in exercising mice.   

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In providing an effective safety and health program effective human resource management is critical. It includes development of accurate job descriptions to take into consideration job duties that may trigger the need for pre-employment evaluations and me

Health and Safety Basics: Workplace Planning and Staffing

July 22, 2014 8:39 am | Articles | Comments

In providing an effective safety and health program effective human resource management is critical. It includes development of accurate job descriptions to take into consideration job duties that may trigger the need for pre-employment evaluations and medical surveillance.

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The Blue Line Cage consists of a wide range of cages, offering flexibility and an automatic watering system. The system offers dual protection for both operators and animals, as well as low maintenance and energy savings. The external self-centering water

Cage with Automatic Watering System

July 22, 2014 8:36 am | Tecniplast S.p.A. | Product Releases | Comments

The Blue Line Cage consists of a wide range of cages, offering flexibility and an automatic watering system.

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Access Technologies Acquires Solomon Scientific Product Lines

July 22, 2014 8:29 am | Access Technologies | News | Comments

Access Technologies, a provider of infusion devices, has announced that it has completed the acquisition of the Solomon Scientific port, catheter and needle product lines.                       

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