Over the past decade, some researchers have been tirelessly testing the effectiveness of early behavioral interventions for autism. Others have been hard at work characterizing and manipulating mouse models of the disorder. Growing up with an ‘auntie’ mouse reverses social and cognitive deficits seen in mice that model one of the most common forms of autism.
Researchers from the University of Auckland and Duke University Medical Center have collaborated...
A study has found that neurons in rats’ brains reacted entirely differently to virtual and real...
Promoting healthy gut microbiota, the bacteria that live in the intestine, can help treat or...
Bioengineers ahave discovered that mouse embryos are contemplating their cellular fates in the earliest stages after fertilization when the embryo has only two to four cells, a discovery that could upend the scientific consensus about when embryonic cells begin differentiating into cell types. Their research used single-cell RNA sequencing to look at every gene in the mouse genome.
Funding Opportunity for Minor Use/Minor Species (MUMS) Development of Drugs to Publish in Early 2015November 25, 2014 10:22 am | News | Comments
The Food and Drug Administration (FDA) will publish a New Funding Opportunity Announcement (FOA) entitled “Minor Use Minor Species Development of Drugs; Research Project Grant (R01)” in early 2015. The new FOA will replace #RFA-FD-12-003, which is set to expire on January 17, 2015.
A protein that stimulates the brain to awaken from sleep may be a target for preventing Alzheimer’s disease, a study by researchers at Washington University School of Medicine in St. Louis suggests.
Using a mouse model of autism, scientists from the University of Chicago identified a malfunctioning neural circuit associated with reduced capacity for motor learning. This appears to arise from an inability to eliminate unneeded neural connections in the brain.
Recent studies have linked dysfunctional mitochondria as one of the pathways causing neuron death. These organelles convert compounds derived from food into the molecules that cells use for energy. Studies suggest that proteins involved in the dynamics of these organelles may play a role in Parkinson’s disease.
Typically, managers dread having to perform employee assessments and experience high anxiety anticipating them. For the employee, too, who is about to undergo a formal performance assessment, the procedure is a high-anxiety producer. So what typically happens is that two very nervous people get together, try to act calm, and just “get through it.” It doesn’t have to be that way.
ALN recently asked readers what the current status of their vivarium was. Click through to see the results.
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For the first time, researchers transplanted bone marrow stem cells into damaged brain tissue while applying lipoic acid (a potent antioxidant), with the aim of improving neuroregeneration in the tissue. This method of repairing brain damage, which combines cellular treatment with drug therapy, has shown positive results, especially in forming blood vessels in damaged areas of the brains of adult laboratory mice.
A lot of research has shown that poor regulation of the serotonin system, caused by certain genetic variations, can increase the risk of developing psychiatric illnesses such as autism, depression, or anxiety disorders.
A gene associated with schizophrenia plays a role in brain development and may help to explain the biological process of the disease, according to new Rutgers research.
While blood draws are critical to monitoring biosecurity or mouse health, they induce stress in mice that can be seen through facial expressions and behavioral patterns. Previous studies have shown that certain bleeding techniques, such as sampling from the tail vein or using blood-sucking bugs, reduce stress. The recently developed dried blood spot (DBS) analysis method may further reduce stress, regardless of sampling technique.
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