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Researchers Digitally Reconstruct Piece of Brain

October 12, 2015 | News | Comments

If you want to learn how something works, one strategy is to take it apart and put it back together again. For 10 years, a global initiative called the Blue Brain Project has been attempting to do this digitally with a section of juvenile rat brain. The project presents a first draft of this reconstruction, which contains over 31,000 neurons, 55 layers of cells, and 207 different neuron subtypes, in Cell.



Virtually Cleansing the Pig Genome

October 12, 2015 10:35 am | News | Comments

In effort to enable organ transplants into humans, researchers have used the CRISPR gene editing technique to inactivate all 62 copies of a retrovirus in a pig cell line, a significant step on the road to generating pig organs for possible xenotransplantation.

Explosion-Proof Hood

October 12, 2015 9:32 am | by Terra Universal, Inc. | Terra Universal, Inc. | Product Releases | Comments

Terra’s explosion-proof hoods provide a safe, particle-free ISO 5 environment, designed for Class I and Class II, Division 1 hazardous locations. Equipped with UL-listed fan/filter module and lighting, they are ideal for working with fumes, flammable vapors, and performing applications in the presence of dust.

The Hidden Hurdles Manager's Must Face

October 8, 2015 4:09 pm | by Martin Seidenfeld, Ph.D. | Articles | Comments

Besides learning the technical skills needed to effectively manage others, would-be managers must come to understand the psychological affect that they, as managers, will have on their employees . . . and how that changed perception will affect them. They must come to accept that at a deep, visceral level, managers are not seen as normal human beings and therefore shouldn’t expect their employees to treat them as such.


Overcoming the Fear of Public Speaking

October 8, 2015 4:00 pm | by Ann Marie Dinkel, RLATG | Articles | Comments

Glossophobia is a really big word for a very common problem-fear of public speaking. According to one source, it is the most common phobia. Anxiety reactions can be as minor as discomfort or can manifest as a full-blown panic attack. Many people avoid public speaking altogether as a protection mechanism. For a trainer, it is difficult to avoid speaking publically unless you work exclusively online.


Risk Characterization

October 8, 2015 3:46 pm | by Stacy Pritt, DVM, MBA, MS, CPIA | Articles | Comments

Risk characterization is the second component of risk assessment. The framework for risk characterization is relatively simple and remains the same know matter what industry or business and organization is in.


The ATA Celebrates Its 60th Anniversary!

October 8, 2015 3:35 pm | by Teresa Woodger | Articles | Comments

The Allied Trade Association (ATA) is an association of independent companies selling products and services to laboratory animal research companies and facilities. For 60 years, the ATA has represented the interest of commercial businesses at National AALAS meetings and, more recently, the LAMA-ATA meetings.


A Global IACUC Council

October 8, 2015 3:22 pm | by Dena Pellecchia | Articles | Comments

When you have an array of variable research operations to consider, how do you create a uniform mindset that is conducive to maintaining flawless animal care, welfare and ethics while respecting the autonomy of multiple different IACUCs or Animal Welfare Bodies (AWBs) in three different countries? You create a Global IACUC Council of course!


Appreciating the Zebrafish

October 8, 2015 2:52 pm | by Helen Kelly | Articles | Comments

Early excitement about Brachydanio rerio is now a full-blown global hum of research activity as the promise of this two inch-long fish is increasingly fulfilled in labs around the world. 


Research Sheds Light on Stem Cells

October 8, 2015 1:55 pm | News | Comments

A Johns Hopkins University biologist has led a research team reporting progress in understanding the mysterious shape-shifting ways of stem cells, which have vast potential for medical research and disease treatment.


Blanket Approach to Asthma Not Ideal

October 8, 2015 1:41 pm | News | Comments

University of Queensland research into the effects of dust mite and cockroach allergens has found that different types of asthma respond differently to a new experimental treatment.


Elephants’ Natural Defenses Against Cancer Hold Molecular Hope for Humans

October 8, 2015 1:32 pm | by Seth Augenstein, Digital Reporter | News | Comments

Elephants have 100 times the cells that humans do. They should also have 100 times the chance of developing cancer. But they don’t – elephants actually rarely ever develop the disease, but it was never known why.


Cells Responsible for Turning Blood Vessels into Muscle Identified

October 8, 2015 12:16 pm | News | Comments

Researchers have identified a new pool of cells as the source of excess smooth muscle that often obstructs blood vessels of patients with pulmonary hypertension. The findings in mice and human tissue set the stage for developing therapies targeting these cells, which may prove to be an important underlying cause of pulmonary hypertension and other heart diseases, the leading cause of death worldwide.


Antioxidants May Accelerate Spread of Skin Cancer

October 8, 2015 12:04 pm | News | Comments

Antioxidants can accelerate the spread of skin cancer, researchers find, stacking up yet more evidence that counters the compounds’ widely-touted, yet controversial anti-cancer benefits. While the study in mice and human cells remains to be confirmed in people, the results caution against excessive or unnecessary intake of antioxidants by melanoma patients.


Decoding What Goes Wrong in Arthritis

October 8, 2015 11:22 am | News | Comments

Scientists have discovered what they believe has the potential to prevent the onset of an aggressive and hard-to-treat form of rheumatoid arthritis. In a new study, a team of immunologists describe how an immune system protein - interleukin-27 - regulates the inflammatory process in lymphoid-rich rheumatoid arthritis, which causes the characteristic symptoms of swollen and painful joints.


NIH Scientists Identify How Normally Protective Immune Responses Kill Neurons

October 8, 2015 11:12 am | News | Comments

Many brain disorders involve the death of neurons, or nerve cells, but how these neurons die is not well understood. A new study in The Journal of Immunology describes how the activation of normally protective immune responses causes nerve cells to die and identifies the protein responsible, providing a potential target for therapeutic intervention.



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