The leading source for today's research animal facilities.
Subscribe to Controlled Environments All

The Lead

Succession Planning and Knowledge Transfer

May 22, 2015 | by Ann Marie Dinkel, RLATG | Articles | Comments

While baby boomers are working longer, at some point they will retire, taking years of historical knowledge with them. This loss of corporate memory is a drain on organizational resources, making succession planning and knowledge transfer essential to business survival.



Experimental Ebola Treatment Boosts Survival in Mice

May 22, 2015 10:00 am | News | Comments

The number of new Ebola cases is tapering off, but the search for new treatments continues. Now, one research team has found potential drug candidates that successfully treated up to 90 percent of mice exposed to the Ebola virus.


Clinical Conversion Kit for MRI Systems

May 21, 2015 10:02 am | by MR Solutions | Product Releases | Comments

A clinical MRI scanner can be transformed into an effective preclinical system using a simple to fit conversion kit from MR Solutions of Guildford, Surrey. The transformation, which can be undertaken in around ten minutes, involves sliding in a carrier system linked to a separate state of the art EVO spectrometer providing superior soft tissue contrast and molecular imaging capabilities.

Molecule Designed to Treat Lung Cancer Shows Promise in Mice

May 21, 2015 9:59 am | News | Comments

A multidisciplinary team has identified a new therapy for lung cancer, the most common cancer worldwide. The treatment involves a molecule, RK-33, that interrupts the cell cycle of lung cancer cells without harming normal cells, and is effective both on its own and in combination with radiation therapy.


Vitamin E Helps with Membrane Repair to Keep Muscles Healthy

May 21, 2015 9:47 am | by Toni Baker, Georgia Regents University and Health System | News | Comments

Vitamin E has long known as a powerful antioxidant, and now scientists have shown that without it, the plasma membrane, which essentially keeps a cell from spilling its contents and controls what moves in and out, cannot properly heal. That’s a big problem for many cells, such as muscle cells, which get membrane tears just from being used.


Cancer Drugs May Hold Key to Treating Down Syndrome and Fragile X Syndrome

May 21, 2015 9:30 am | by Ian Demsky, University of Michigan | Videos | Comments

A class of FDA-approved cancer drugs may be able to prevent problems with brain cell development associated with disorders including Down syndrome and Fragile X syndrome, researchers at the University of Michigan Life Sciences Institute have found.


Age-reversal Effects of 'Young Blood' Molecule GDF-11 Called Into Question

May 21, 2015 9:30 am | News | Comments

The vampiric exchange of young blood and old blood has long been reported to have anti-aging effects, but it was in 2013 when researchers first linked GDF-11, a molecule that circulates in the blood, to this effect. Now, an analysis that set out to see how GDF-11 works in the muscles found just the opposite.


What kind of surgical and medical equipment and supplies do you use in your vivarium?

May 21, 2015 9:28 am | by Elizabeth Doughman, Editor-in-Chief | Articles | Comments

ALN recently asked readers what types of surgical and medical equipment and supplies they use in their vivariums. Click here to see the results.                  


Nesting Material

May 20, 2015 3:33 pm | by The Andersons Lab Bedding Products | The Andersons Lab Bedding Products | Product Releases | Comments

Bed-r’Nest™ is now available in a 4 gram and 8 gram size of portion controlled, easy-to-dispense nesting material that requires no tearing, pulling or prepping. Made of 100% virgin kraft paper, Bed-r’Nest is designed to resemble the thin strands of grass and other materials mice instinctively use to build their nests in nature. With no outer shell or material to work through, Bed-r’Nest makes nesting material immediately available to animals.


Skipping Meals Linked to Abdominal Weight Gain in Mice

May 20, 2015 10:26 am | by Emily Caldwell, The Ohio State University | News | Comments

In a new study, mice that ate all of their food as a single meal and fasted the rest of the day developed insulin resistance in their livers. The mice also showed greater weight gain around their middles than mice that were free fed, which has been associated with insulin resistance and risk for type 2 diabetes and heart disease.


Gel Filled with Nanosponges Cleans Up MRSA Infections in Mice

May 20, 2015 9:58 am | by Liezel Labios, University of California, San Diego | News | Comments

Nanoengineers at the University of California, San Diego developed a gel filled with toxin-absorbing nanosponges that could lead to an effective treatment for skin and wound infections caused by MRSA, an antibiotic-resistant bacteria. This nanosponge-hydrogel minimized the growth of skin lesions on mice infected with MRSA – without the use of antibiotics.


Bigger Capsules May Be Key for Treating Type 1 Diabetes in Animal Models

May 20, 2015 9:47 am | by Sharon Parmet, University of Illinois at Chicago | News | Comments

Changing the size of cell-carrying spheres may surmount the difficulties that have bedeviled diabetes researchers trying to ferry insulin-producing islet cells into hosts as a way to treat type 1 diabetes. New findings published in the journal Nature Materials suggest that for the spherical capsules, bigger may be better.


Exposure to Alcohol Changes a Mouse Offspring's Brain Even in Early Pregnancy

May 20, 2015 9:34 am | by Elizabeth Doughman, Editor-in-Chief | News | Comments

The offspring of mice who drank alcohol in early pregnancy showed changes in gene function in their brain and other tissues, according to a recent study from the University of Helsinki. The changes were present in the offspring of mice exposed to alcohol in the time period corresponding to the human gestational weeks 3-6, a time period where many mothers-to-be are typically unaware of the fact that they are pregnant.


Spotlight on Animal Welfare

May 20, 2015 9:33 am | by Stacy Pritt, DVM, MS, MBA, CPIA, DACAW | Articles | Comments

In laboratory animal science, we are very concerned about animal health and behavior which makes us naturally very cognizant of animal welfare. However, we also need to be aware of current concepts in the field of animal welfare and how those concepts should be appropriately applied.


Art's-Way Scientific Wins Modular Building Institute Award For Iowa State University Transgenic Swine Facility

May 19, 2015 5:01 pm | Art's Way Scientific, Inc. | News | Comments

Art's Way Manufacturing Co., Inc. announces that Art's-Way Scientific was awarded a 2015 Award of Distinction by the Modular Building Institute (MBI), at the annual MBI World of Modular Conference in Las Vegas, NV.  The award winning modular transgenic swine facility was designed, manufactured and installed for Iowa State University's Zumwalt Station Farm in Ames, IA.

An important link between the human body clock and the immune system has relevance for better understanding inflammatory and infectious diseases. A critical white blood cell called the macrophage, when exposed to bacteria, makes the biological clock insid

Immune System Controls Biological Clock in Times of Infection

May 19, 2015 10:09 am | by Penn Medicine | News | Comments

An important link between the human body clock and the immune system has relevance for better understanding inflammatory and infectious diseases. A critical white blood cell called the macrophage, when exposed to bacteria, makes the biological clock inside the macrophage stop, allowing it to become inflamed.



You may login with either your assigned username or your e-mail address.
The password field is case sensitive.