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The Lead

Dog Study Provides Answers About Brain Tumor Development

May 26, 2016 | by Elizabeth Doughman, Editor-in-Chief | News | Comments

Dogs are an excellent animal model for studying cancer, a recent study published in PLOS Genetics found. The research identified genes that could possibly play a role in the development of brain cancer in both dogs and humans.

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Breast Cancer Cells Lose Hide-and-Seek Game

May 26, 2016 2:11 pm | by Duke Medicine News and Communications | News | Comments

Scientists have identified a molecular key that breast cancer cells use to invade bone marrow in mice, where they may be protected from chemotherapy or hormonal therapies that could otherwise eradicate them.

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EZ-UP Modular Softwall Cleanroom

May 26, 2016 11:47 am | by Terra Universal, Inc. | Terra Universal, Inc. | Product Releases | Comments

Terra Universal introduces its EZ-UP Cleanroom™, a modular softwall enclosure that meets ISO 7 cleanliness requirements. The flexible, plastic panels surround a powder-coated steel frame and connect using either industrial-grade zippers or radio-frequency (RF) welding. Softwall cleanrooms are often a more economical alternative to modular hardwall rooms, or permanent bricks-and-mortar enclosures.

USDA Issues Historic Fine Against Biotech Company in Animal Welfare Settlement

May 25, 2016 1:14 pm | by Lauren Scrudato, Associate Editor, Laboratory Equipment | News | Comments

Santa Cruz Biotechnology, Inc. has agreed to pay a $3.5 million fine, and revoke its research registration and dealer license in accordance with terms of a legal settlement with the U.S. Dept. of Agriculture.

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Targeted Liver Cancer Treatment on the Horizon

May 25, 2016 1:10 pm | by University of Eastern Finland | News | Comments

A new molecular mechanism can be used to inhibit the growth of hepatocellular carcinoma, which is the most common liver cancer.

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Teenage Brain Changes May Ease Traumatic Memories

May 25, 2016 12:57 pm | by Weill Cornell Medical College | News | Comments

Unique connections in the adolescent brain make it possible to easily diminish fear memories and avoid anxiety later in life. The findings may have important implications for the treatment of trauma and anxiety disorders.

An Easier Way to Study Blood Cancers

May 25, 2016 12:42 pm | by Christopher Vaughan, Stanford University | News | Comments

Researchers have developed a method of implanting cells to create a human bone-like structure in mice. This allows investigators to study a whole host of blood cancers and other diseases that they had trouble studying before.

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Dog Study Identifies Genes Behind Three Rare Diseases

May 25, 2016 12:03 pm | by Elizabeth Doughman, Editor-in-Chief | News | Comments

Three canine genes for Caffey, Raine, and van den Ende-Gupta syndrome have been identified in a new study published in PLOS Genetics. These discoveries will help further the development of rare disease diagnostic and treatments, as well as veterinary diagnostics and breeding programs.

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Exploring the Role of Transcription Factors in Lymphatic Diseases

May 24, 2016 1:27 pm | by Sarah Plumridge, Northwestern University Feinberg School of Medicine | News | Comments

In a recent study, scientists identified a pathway through which transcription factor proteins regulate lymphangiogenesis, the formation of lymphatic vessels from pre-existing lymphatic vessels. These results suggest a new mechanism for diseases associated with lymphatic vessels, which transport fluid out of tissues as part of the body’s lymphatic system.

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Negative Enzyme Produces Positive Results

May 24, 2016 12:55 pm | by University of Geneva | News | Comments

Chemistry has provided many key tools and techniques to the biological community in the last twenty years. We can now make proteins that Mother Nature never thought of, image unique parts of live cells and even see cells in live animals.

Triple-Therapy Cocktail Combats Breast Tumors

May 24, 2016 12:49 pm | by Johns Hopkins Medicine | News | Comments

In a new study using mice and lab-grown human cells, a scientific team led by Johns Hopkins Kimmel Cancer Center researchers show how a triple-drug cocktail can shrink triple-negative breast cancers by killing off cancer cells and halting new tumor growth.

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Study Offers Possible Solution for Age-related Memory Issues

May 24, 2016 12:39 pm | by Elaine Schmidt, UCLA | News | Comments

Neuroscientists boost ability of aging brain to recapture links between related memories.

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TurnKey Award Winners Announced

May 24, 2016 12:36 pm | by Elizabeth Doughman, Editor-in-Chief | Articles | Comments

The TurnKey Awards were presented to the 2016 winners at the TurnKey Conference on May 24th at the Gaylord National Harbor Resort and Convention Center in Oxon Hill, MD (Washington, DC). The awards, given by ALN Magazine are in recognition of excellence in two categories: teamwork and facility design.

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Nano-sized Trojan Horses Battle Inflammation

May 24, 2016 11:48 am | by Houston Methodist Research Institute | News | Comments

Nanosized Trojan horses created from a patient’s own immune cells have successfully treated inflammation by overcoming the body’s complex defense mechanisms, perhaps leading to broader applications for treating diseases characterized by inflammation, such as cancer and cardiovascular diseases. "Personalized" DXM-loaded leukosomes were used to treat inflammation in mice.

Fruit Flies Show Why Staying Awake Makes Us Tired

May 23, 2016 1:03 pm | by Johns Hopkins Medicine | News | Comments

Studying fruit flies, whose sleep is remarkably similar to that in people, researchers say they’ve identified brain cells that are responsible for why delaying bedtime creates chronic sleepiness.

Dietary Experiments Enable Faster Colorectal Cancer Detection

May 23, 2016 12:43 pm | by European Society of Human Genetics | News | Comments

Work in genetically-engineered mice has helped to reveal the role played by a Western-style diet, rich in fat and low in fiber, vitamin D and folate, in the development of colorectal cancer.

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