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Using Positive Reinforcement to Motivate Employees

April 24, 2015 | by Martin Seidenfeld, Ph.D. | Articles | Comments

You’ve probably heard it many times, the command to “catch ‘em doing something right!” There’s a good reason this has become a common catchphrase. It’s because “catching” your employee doing something right—performing well—provides a golden opportunity for you to reinforce that “right” behavior.

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Gene Associated with Rare Disease Determines How Body Processes Pain

April 24, 2015 10:13 am | News | Comments

The researched studied the way neural circuits transform harmful stimuli into the perception of pain. More precisely, it examined the gene Lmx1b and its involvement in pain processing. Mutations in this gene also cause a rare human disease called the Nail-patella syndrome (NPS), which is characterized by limb and kidney malformations. More importantly, NPS patients show reduced pain responses.

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Porcine Study Aimed at Engineering More Natural and Durable Replacement Heart Valves

April 24, 2015 9:51 am | News | Comments

With a $450,000 grant from the National Institutes of Health and using porcine cell valves, researchers at Worcester Polytechnic Institute will analyze how mechanical forces and cellular growth factors affect the growth and development of human heart valves to advance the long-term goal of using tissue engineering to develop replacement valves that are more natural and longer-lasting than current replacement valves.

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Protein that Serves a Brake on Inflammation Identified

April 23, 2015 10:44 am | News | Comments

Researchers have identified a protein that offers a new focus for developing targeted therapies to tame the severe inflammation associated with multiple sclerosis (MS), colitis, and other autoimmune disorders. St. Jude Children’s Research Hospital scientists led the study which appears this week in the scientific journal Immunity.

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Immune System Protein Regulates Sensitivity to Bitter Taste

April 23, 2015 10:30 am | News | Comments

New research from the Monell Center reveals that tumor necrosis factor (TNF), an immune system regulatory protein that promotes inflammation, also helps regulate sensitivity to bitter taste. The finding may provide a mechanism to explain the taste system abnormalities and decreased food intake that can be associated with infections, autoimmune disorders, and chronic inflammatory diseases.

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Contec, Inc. Awarded for Outstanding Safety Practices

April 23, 2015 10:15 am | Contec, Inc. | News | Comments

Contec, Inc. was recently awarded a 2015 Certificate of Safety Achievement by the State of South Carolina’s Labor, Licensing, and Regulation Department “for outstanding efforts in the promotion of Industrial Safety and Health, with such efforts resulting in the lessening of human suffering and the reduction of economic waste 1.2 million hours without a lost time injury or illness”.

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Maternal Stress Increases Development of Fetal Neuroblastoma in Mice

April 23, 2015 10:12 am | News | Comments

While genetics play a substantial role in development of neuroblastoma, scientists say that something else is in play that elevates the risk: stress. Researchers from the Georgetown University Medical Center have shown in mice genetically predisposed to develop neuroblastoma that maternal stress can push onset of the cancer.

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Omission Cues Suppress Relapse in Animal Models of Drug Addiction

April 23, 2015 10:04 am | News | Comments

A new study is researching the brain mechanisms behind the cues signaling the unavailability of drugs or alcohol (“omission cues”) that can actually suppress relapse in well-established animal models of drug addiction. This research could not only uncover fundamental workings of the brain in behavioral inhibition, but could also point to new methods for helping people resist relapse.

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Workplace Exposure Limits for Halogenated Anesthetic Agents

April 23, 2015 9:41 am | by Brett Field | Articles | Comments

In the past 25 years, halogenated anesthetic agents, primarily isoflurane and sevoflurane, have become indispensable tools in laboratory animal science. Since the beginning of their widespread clinical use, the health effects of halogenated agents have been the subject of numerous studies and by now, the importance of monitoring and limiting operator exposure has become common knowledge.

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Brain Circuitry Responsible for Anxiety in Smoking Cessation Identified

April 22, 2015 10:59 am | by Sandra Gray, University of Massachusetts Medical School | News | Comments

In a promising breakthrough for smokers who are trying to quit, neuroscientists at UMass Medical School and The Scripps Research Institute have identified circuitry in the brain responsible for the increased anxiety commonly experienced during withdrawal from nicotine addiction.

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How Blood-oxygen Levels Regulate Air Intake

April 22, 2015 10:47 am | News | Comments

A new study describes the precise mechanism that cells in the carotid bodies use to detect oxygen levels in the blood as it flows toward the brain. The cells translate that taste test into signals, sent through the carotid sinus nerve, a branch of the glossopharyngeal nerve, to stimulate or relax breathing rates.

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Cross-talk Leaves Pancreatic Cancer Cells Defenseless Against Viruses

April 22, 2015 10:09 am | News | Comments

Ottawa researchers have unlocked a way to make pancreatic cancer cells more vulnerable to cancer-killing viruses, known as oncolytic viruses. The scientists have discovered how they can exploit the communication, or cross-talk, between pancreatic cancer and a specific cell type that supports the tumor. They found that this cross-talk weakens the ability of both cell types to fight off cancer-fighting viruses.

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Zipping in Fruit Flies Furthers Understanding of How Wounds Heal

April 22, 2015 9:47 am | News | Comments

The events leading to skin closure during wound healing have been unclear for many years. A new study used fruit fly embryos as a model system to understand this process. During development, fruit fly embryos have a large opening in the skin on their back that must fuse. This process is called zipping, because two sides of the skin are fastened in a way that resembles a zipper that joins two sides of a jacket.

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Does Your Facility Outsource for Any of the Following Services?

April 22, 2015 9:26 am | by Elizabeth Doughman, Editor-in-Chief | Articles | Comments

ALN recently asked subscribers what kind of services their facility outsources for. Click here to see the answers.                       

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Complimentary Lab Tour Added to 2015 TurnKey Conference

April 21, 2015 4:57 pm | by Elizabeth Doughman, Editor-in-Chief | News | Comments

If you haven't signed up yet to attend the 2015 TurnKey Conference - here's one more reason to attend. All registered 2015 TurnKey Conference attendees are invited to tour Innovive Inc.'s corporate headquarters and state-of-the-art manufacturing facility located in San Diego, CA.

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A novel approach that allows real-time imaging of the immune system’s response to the presence of tumors — without the need for blood draws or invasive biopsies — offers a potential breakthrough both in diagnostics and in the ability to monitor efficacy o

Imaging Immune System in Mice Detects Tumors

April 21, 2015 11:28 am | by Matt Fearer, Whitehead Institute | News | Comments

A novel approach that allows real-time imaging of the immune system’s response to the presence of tumors — without the need for blood draws or invasive biopsies — offers a potential breakthrough both in diagnostics and in the ability to monitor efficacy of cancer therapies.

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