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The Lead

Is There Room to Improve Surgical Skills and Training in Rodents?

April 18, 2014 8:20 am | by Szczepan Baran, Elizabeth Johnson, and Matthew Flegal | Articles | Comments

Mice are the most prevalent animal utilized within the biomedical field, and, in the early 1980s, the development of transgenic technologies which lead to the availability of genetically engineered mice further expanded their usefulness within fields of immunology, oncology, physiology, pathology, and neuroscience.



Four TurnKey Conference Sessions Eligible for GBCI Credit

April 18, 2014 1:46 pm | News | Comments

Earn GBCI credit at the 2014 TurnKey Conference, held May 13-14 in National Harbor, MD by participating in one of the following sessions: Streamlining the Vivarium Facility Performance Verification Process, Are We There Yet? Bridging the Gap between Construction and Operation, Planning for the Unthinkable in Vivarium Design, and Facility Containment & Extreme Events: A Risk-Based Approach.


Innovative Strategy Facilitates Organ Repair

April 18, 2014 12:39 pm | by Inserm | News | Comments

A team of researchers has just demonstrated that the principle of adhesion by aqueous solutions of nanoparticles can be used in vivo to repair soft-tissue organs and tissues.                     


Disinfection System

April 18, 2014 8:18 am | Quip Laboratories, Inc. | Product Releases | Comments

The Halo Disinfection System™, a supplemental surface disinfection system with efficacy against 99.99% of bacteria, viruses, and fungi, consists of the HaloFogger™, a dry fogging device, Halo Disinfectant, a power management strip, and reusable telescopic HVAC vent covers.


Jump-starting Natural Resilience Reverses Stress Susceptibility

April 17, 2014 3:41 pm | by NIH | News | Comments

Scientists have traced vulnerability to depression-like behaviors in mice to out-of-balance electrical activity inside neurons of the brain’s reward circuit and experimentally reversed it – but there’s a twist.           


April 2014 ALN

April 17, 2014 1:45 pm | Digital Editions | Comments

Check out the ALN Magazine April 2014 Digital Edition!


Nasal Spray Could Protect against Any Flu

April 17, 2014 1:40 pm | by Univ. of St. Andrews | News | Comments

Scientists have developed a novel treatment that could protect against current, future and even pandemic strains of flu. The preventative treatment could be used as a "frontline defence" before an effective flu vaccine is developed.     


Essential Protein Needed for Fertilization

April 17, 2014 1:25 pm | by Wellcome Trust Sanger Institute | News | Comments

Researchers have discovered interacting proteins on the surface of the sperm and the egg essential to begin mammalian life. These proteins, which allow the sperm and egg to recognize one another, offer new paths towards improved fertility treatments and the development of new contraceptives.


Cancer Drugs Block Dementia-linked Brain Inflammation in Mice

April 17, 2014 1:11 pm | by Univ. of California, Irvine | News | Comments

A class of drugs developed to treat immune-related conditions and cancer — including one currently in clinical trials for glioblastoma and other tumors — eliminates neural inflammation associated with dementia-linked diseases and brain injuries.


Cause of Eye Mobility Disorder Developed in Mouse Models

April 17, 2014 1:03 pm | by Steve Kehoe, Univ. of Iowa | News | Comments

Researchers have developed a mutated mouse model that mimics the human mutation of an eye mobility disorder in order to understand why it occurs.                             


TurnKey Session of the Week: Facility Containment & Extreme Events: A Risk-Based Approach

April 17, 2014 8:13 am | News | Comments

The major goal of a bio-containment operation is to maintain the primary and secondary facility containment systems, preventing the release of pathogenic material. During tornado events, extreme internal and external air pressure differentials will test the design parameters of structural and enclosure systems. This presentation will identify, compare, and define a risk-based approach to the most vulnerable of these systems.


Combination Isolator/IVC

April 17, 2014 8:10 am | TECNIPLAST | Product Releases | Comments

The ISO Positive Housing System effectively combines the safety and protection of an isolator with the advantages of an IVC system: density, flexibility, ergonomics.


UofL Has 25,000 Rodents on Its Health Sciences Campus (For Research)

April 16, 2014 3:31 pm | News | Comments

The University of Louisville's health sciences campus has thousands of rats and mice — and officials are not only OK with it, they're planning to soon get the rodents new homes through an allotment from the Kentucky General Assembly.   


Technique Reverse-engineers Developing Lung

April 16, 2014 1:08 pm | by Tom Abate, Stanford Univ. | News | Comments

In a feat of reverse tissue engineering, researchers have begun to unravel the complex genetic coding that allows embryonic cells to proliferate and transform into all of the specialized cells that perform a myriad of different biological tasks.  


Hair from Infant Monkeys Gives Clues about Life in the Womb

April 16, 2014 12:36 pm | by Kelly April Tyrrell, Univ. of Wisconsin-Madison | News | Comments

A team researchers show in a study of rhesus monkeys that hair can reveal the womb environment in which an infant formed.                                     


Mouse Model Would Have Predicted Toxicity of Fatal Drug

April 16, 2014 12:22 pm | by PLOS | News | Comments

Over 20 years after the fatal fialuridine trial, a study demonstrates that mice with humanized livers recapitulate the drug's toxicity.                                 



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