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The use of specific pathogen free (SPF) laboratory animals in biomedical research increases demand for sterilized feeds for breeding and maintenance purposes. In many breeding units autoclave sterilization of commercial diets is preferentially employed. T

Autoclaving Laboratory Feeds

November 21, 2014 | by Anna Tuśnio, Marcin Barszcz, Marcin Taciak, & Barbara Pastuszewska | Articles | Comments

The use of specific pathogen free (SPF) laboratory animals in biomedical research increases demand for sterilized feeds for breeding and maintenance purposes. In many breeding units autoclave sterilization of commercial diets is preferentially employed. This relatively inexpensive and convenient method comprises heat, pressure, and steam treatment of pelleted feeds.

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 Scientists have discovered that genes switch off as memories are being formed, allowing for new connections between nerve cells. The discovery could eventually lead to a key for treating conditions such as autism and dementia.

Bee Brains Offer Insights into Human Memory Formation

November 21, 2014 3:07 pm | by University of Queensland | News | Comments

Scientists have discovered that genes switch off as memories are being formed, allowing for new connections between nerve cells. The discovery could eventually lead to a key for treating conditions such as autism and dementia.       

Researchers working with mice have uncovered a potential clue to polydactyly a birth defect involving extra fingers on the hand or extra toes on the feet. The researchers have found that a mouse version of polydactyly results from a malfunction of the cel

Mouse Study Reveals Potential Clue to Extra Fingers or Toes

November 21, 2014 2:50 pm | by NIH | News | Comments

Researchers working with mice have uncovered a potential clue to polydactyly a birth defect involving extra fingers on the hand or extra toes on the feet. The researchers have found that a mouse version of polydactyly results from a malfunction of the cellular machinery that processes one of the cell’s internal transportation vehicles.

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Harvard Apparatus surgical instrument kits, configured from the Harvard Apparatus high quality surgical tool line, combine the most popular pieces for both general and specific surgical applications.

Surgical Instrument Kits

November 21, 2014 8:47 am | Harvard Apparatus | Product Releases | Comments

Harvard Apparatus surgical instrument kits, configured from the Harvard Apparatus high quality surgical tool line, combine the most popular pieces for both general and specific surgical applications.

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Researchers have found that a growth factor can regenerate damaged peripheral   nerves without causing the growth of new blood vessels — making it a unique   candidate to treat nerve damage in areas of the body where the proliferation of   blood vessels w

Damaged Nerves Regenerated without Blood Vessel Growth

November 20, 2014 10:18 am | by Sharon Parmet, University of Illinois at Chicago | News | Comments

Researchers have found that a growth factor can regenerate damaged peripheral nerves without causing the growth of new blood vessels — making it a unique candidate to treat nerve damage in areas of the body where the proliferation of blood vessels would be a drawback. 

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Looking across evolutionary time and the genomic landscapes of humans and mice, an international group of researchers has found powerful clues to why certain processes and systems in the mouse are so different from those in people. Building on years studi

Mouse Genome Similar and Very Different from Human Genome

November 20, 2014 10:06 am | by NIH/National Human Genome Research Institute | News | Comments

Looking across evolutionary time and the genomic landscapes of humans and mice, an international group of researchers has found powerful clues to why certain processes and systems in the mouse are so different from those in people. Building on years studies, they have developed a resource that can help scientists better understand how similarities and differences between mice and humans are written in their genomes.

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HEMCO Modular CleanLabs feature a modular construction design that is cost effective and time efficient compared to traditional construction.  An entire laboratory workspace is pre-engineered including the structure and the lab furniture/fume hoods to out

Modular CleanLabs

November 20, 2014 8:20 am | Hemco | Product Releases | Comments

HEMCO Modular CleanLabs feature a modular construction design that is cost effective and time efficient compared to traditional construction. An entire laboratory workspace is pre-engineered including the structure and the lab furniture/fume hoods to outfit the interior. 

By manipulating the circadian clocks of Siberian hamsters, scientists may have identified a brain structure that disrupts memory when circadian rhythms fall apart, as they often do in patients with neurodegenerative diseases such as Alzheimer's.

Link between Memory Deficit and Misfiring Circadian Clock

November 20, 2014 8:04 am | by Bjorn Carey, Stanford University | News | Comments

By manipulating the circadian clocks of Siberian hamsters, scientists may have identified a brain structure that disrupts memory when circadian rhythms fall apart, as they often do in patients with neurodegenerative diseases such as Alzheimer's.

In what is likely to be a major step forward in the study of influenza, cystic fibrosis and other human diseases, an international research effort has sequenced the ferret genome. The sequence was then used to analyze how the flu and cystic fibrosis affec

Ferret Genome Holds Clues to Respiratory Diseases

November 20, 2014 8:03 am | by Michael McCarthy, University of Washington | News | Comments

In what is likely to be a major step forward in the study of influenza, cystic fibrosis and other human diseases, an international research effort has sequenced the ferret genome. The sequence was then used to analyze how the flu and cystic fibrosis affect respiratory tissues at the cellular level.

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It all started in 2008. The goal: attract top investigators -- Ph.D.s, Ph.D. candidates, professors, and post grads — and fundamentally advance knowledge of cancer and other complex diseases. This is not a classroom building; it is a research facility.

Marsico Hall Brings Together Top Researchers and Best Medical Technology

November 19, 2014 12:27 pm | by Biomedical Research Imaging Center | News | Comments

It all started in 2008 at the University of North Carolina (UNC) School of Medicine. The goal: attract top investigators -- Ph.D.s, Ph.D. candidates, professors, and post grads — and fundamentally advance knowledge of cancer and other complex diseases. This is not a classroom building; it is a research facility.

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For over a decade, animal care guidelines have emphasized the need for continuous, electronic monitoring of vivariums and related facilities.1 To meet this need, many products offer continuous monitoring and reporting of environmental conditions such as t

Experiences with Wireless Environmental Sensors in Animal Care Facilities

November 19, 2014 12:11 pm | by Robert L. Harris, Robert S. Moore, and Richard P. Martin | Articles | Comments

For over a decade, animal care guidelines have emphasized the need for continuous, electronic monitoring of vivariums and related facilities. To meet this need, many products offer continuous monitoring and reporting of environmental conditions such as temperature, humidity, airflow, and light levels. Unfortunately, these can be costly to install and operate, which is beyond the resources of many facilities.

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The Sarstedt S-Monovette® is an enclosed multiple-sampling blood collection system designed with safety in mind. All tubes are plastic with screw caps, which minimizes the risk of breakage and aerosol formation when caps are removed.

Blood Collection System

November 19, 2014 12:08 pm | Sarstedt, Inc. | Product Releases | Comments

The Sarstedt S-Monovette® is an enclosed multiple-sampling blood collection system designed with safety in mind. All tubes are plastic with screw caps, which minimizes the risk of breakage and aerosol formation when caps are removed. 

Researchers have discovered how a previously unknown hormone serves as a messenger from fat cells to the liver and are investigating the potential of developing a new treatment for metabolic disorders.

Hormone Prohibits Metabolic Disorders in Mice

November 19, 2014 11:59 am | by University of Michigan | News | Comments

Researchers have discovered how a previously unknown hormone serves as a messenger from fat cells to the liver and are investigating the potential of developing a new treatment for metabolic disorders.              

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Scientists have identified a novel delivery platform by which an antisense molecule — akin to the mirror image of the microRNA — can be used to exploit a unique feature of the tumor microenvironment and thereby gain access to cancer cells.

microRNA Silenced to Target Tumors in Mouse Model

November 19, 2014 11:43 am | by Beth Israel Deaconess Medical Center | News | Comments

Scientists have identified a novel delivery platform by which an antisense molecule — akin to the mirror image of the microRNA — can be used to exploit a unique feature of the tumor microenvironment and thereby gain access to cancer cells.   

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A team of scientists have found that a particular set of cells in a small region of the brain are responsible for memory problems after sleep loss. By selectively increasing levels of a signaling molecule in these cells, the researchers prevented mice fro

Memory Problems Caused by Sleep Deprivation Prevented in Mice

November 19, 2014 11:26 am | by University of Pennsyvania | News | Comments

A team of scientists have found that a particular set of cells in a small region of the brain are responsible for memory problems after sleep loss. By selectively increasing levels of a signaling molecule in these cells, the researchers prevented mice from having memory deficits.

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Scientists from Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) in Japan have developed an advanced imaging system to identify cells responsible for storing memory within a tiny worm. Their study not only offers a new way to ide

Brain Cells Responsible for Memory Mapped in Worms

November 19, 2014 10:53 am | by Kyoto University | News | Comments

Scientists from Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) in Japan have developed an advanced imaging system to identify cells responsible for storing memory within a tiny worm. Their study not only offers a new way to identify molecular substrates of memory but may also one day lead to understanding how memory loss occurs in humans.

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