The use of cages and racks, and their associated accessories and cage wash equipment continue to be used in the majority of animal research facilities, according to a September 2014 survey conducted by ALN World. Ninety-five percent of respondents use cages in their facility, while 83% indicated that they use racks and 83% use cage and rack washers in their vivarium.
Researchers have found that male and female brains respond in remarkably different ways to...
Across the animal kingdom, it’s not uncommon for pregnancy to change an expectant mom’s behavior...
In a discovery that might ring true even for some humans, researchers have shown that male brains — at least in nematodes — will suppress the ability to locate food in order to instead focus on finding a mate.
The U.S. Food and Drug Administration issued today draft Guidance for Industry #227: Two-Phased Chemistry, Manufacturing, and Controls (CMC) Technical Sections, with recommendations for ways animal drug sponsors can submit chemistry, manufacturing, and controls (CMC) data to the agency to improve the efficiency of the New Animal Drug Application (NADA) review process.
Respiratory Syncytial Virus causes severe respiratory tract infections and worldwide claims the lives of 160,000 children each year. Scientists have succeeded in developing a promising vaccination strategy to counteract this common virus infection.
The Zigg is made with primates in mind and is a large toy for the toughest chewers.
Soiled bedding is difficult to handle because of the dense, sticky nature.
The “Rabbit Hole” Vertical Socialization and Foraging System (patent pending) is a rotating floor panel which allows primates to utilize the entire vertical space of the cage unit without increasing cage footprint.
Aspen is a hard wood with short dense fibers that do not splinter; Aspen is known not to produce any volatile compounds making it a good choice for animal bedding and enrichment products.
The researchers found that mice lacking the gene IQGAP1, which codes for a protein expressed in airway smooth muscle, had increased resistance to airflow during mechanical ventilation; they then found that rings of airway dissected from IQGAP1-knockout mice contract much more than those from normal mice. This data suggests that the IQGAP1 protein normally prevents airway contraction.
The experimental vaccines—based on rabies virus vaccines currently used in people and in animals—contain either a killed or a live, attenuated rabies virus engineered to produce an Ebola protein. The killed, or inactivated, vaccine is being developed to prevent rabies and Ebola infection in people, while the live, attenuated vaccine is intended for use in African wildlife to help prevent Ebola virus transmission from animals to people.
Researchers from the UNC School of Medicine have discovered that cells called fibroblasts, which normally give rise to scar tissue after a heart attack, can be turned into endothelial cells, which generate blood vessels to supply oxygen and nutrients to the injured regions of the heart, thus greatly reducing the damage done following a heart attack.
Research has discovered that controlling levels of the human enzyme PCSK9 could be the difference between life and death for patients with severe sepsis.
The ALN Magazine October 2014 digital edition is here. Check out our new design.
A team of scientists has found that disabling the function of a single protein for as little as a week allows the brains of adult mice to form new synaptic connections.
A new study provides the first biological evidence that neurons are finely “tuning” their own molecular-level machinery to regulate this flow of ions and thus their electrical charge.