The growth of metastases in lymph nodes, the most common site of cancer spread, does not require new blood vessels, but instead takes advantage of existing blood vessels, according to a new study using mice from researchers at Massachusetts General Hospital. This finding helps explain why the use of antiangiogenesis drugs that block the growth of new blood vessels has failed in clinical trials.
A scientist who faked results of an experimental HIV vaccine in rabbits to make it appear he had...
Mice that have a genetic version of mitochondrial disease can easily be mistaken for much older...
A new study found that tumors that resemble six-day-old mouse embryos are more prone to...
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have found that a type of genetic material called “microRNA” plays surprisingly different roles in the formation of memory in animal models. In some cases, these RNAs increase memory, while others decrease it.
Researchers at the RIKEN Brain Science Institute in Japan have discovered a key mechanism underlying how animals keep track of the seasons. The study shows how circadian clock machinery in the brain encodes seasonal changes in daylight duration through GABA activity along with changes in the amount of chloride located inside certain neurons.
A new study from Indiana University provides evidence in mice that males may play a positive role in the development of offspring’s brains starting before pregnancy.
A new report suggests that a common molecule found in higher animals, including humans, affects brain structure. The study, involving mice, shows that small changes in how sialic acid attaches to cell surfaces result in damaging effects on brain structure, poor motor skills, hyperactivity, and difficulty in learning.
It is well known that muscles need resistance to maintain optimal health, and when they do not have this resistance, they deteriorate. A new report using mice, however, suggests that this might not be true for all muscles, offering hope that there may be ways to preserve muscle mass and strength for individuals in low-resistance environments, whether it be the microgravity of space, extended periods in a hospital bed, or behind a desk.
The warm temperature on a summer’s day is often a time for relaxing, but researchers from the University of Leicester have suggested that a ‘thermosensory’ gene could be responsible for changes in behavior in different climates, based on research in fruit flies.
University of Maryland School of Medicine scientists and Regeneron Pharmaceuticals, Inc., have discovered and validated two therapeutics that show early promise in preventing and treating the MERS virus, which can cause severe respiratory symptoms, and has a death rate of 40 percent. These therapeutics are the first to succeed in protecting and treating animal models of the disease.
A common filter-feeding marine invertebrate found in coral reefs is able to eject and regenerate its gut within 12 days and rebuild it's branchial sac within 19 days, according to a new study published in Scientific Reports. This finding could lead to promising new avenues in human soft tissue regeneration research.
The influenza virus can be lethal to those who are infected. But what is often just as dangerous is the body’s own reaction to the virus. Now, a researcher has for the first time uncovered new details about how this response plays out.
Researchers have identified a mechanism that explains why some mutations can be disease-causing in one genome but benign in another.
Research has revealed for the first time that pain is processed in male and female mice using different cells.
Hermansky-Pudlak syndrome patients suffer symptoms including albinism, visual impairment, and slow blood clotting, but what makes some versions of the genetic condition fatal is that patients with some forms of the disease develop severe and progressive lung scarring. A new study explains what appears to be going wrong and demonstrates two possible therapeutic strategies in lab experiments.
Laboratories that test chemicals for neurological toxicity could reduce their use of laboratory mice and rats by replacing these animal models with tiny aquatic flatworms known as freshwater planarians.
The enzyme IDO helps reduce inflammation in cells damaged by kidney disease in an animal model, according to a new study from Georgia Regents University. IDO also reduced inflammation in human kidney tissue.
PRI-Bio has been selected by McCarthy/Mortenson and the U.S. Department of Homeland Security to provide multiple bio-hazardous waste decontamination systems for the $835 million National Bio and Agro-Defense Facility, a DHS Science and Technology Directorate project located in Manhattan, Kansas.