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Commissioning Verification and Validation

July 23, 2014 | by Gilles Tremblay and Spencer Andrews | Articles | Comments

One of the most critical challenges facing today’s research facilities is the acquisition of regulatory compliance—that stamp of approval that defines an institution as highly qualified, safe and desirable for the demands and challenges of complex and highly technical research.

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Pre-filled Water Bottles

July 23, 2014 8:27 am | Innovive, Inc. | Product Releases | Comments

Aquavive® Pre-Filled Water Bottles for mouse and rat eliminate washing and processing steps from vivarium operations.

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Scientists have generally believed that HIV and its monkey equivalent, SIV, gain a permanent foothold in the body very early after infection, making it difficult to completely eliminate the virus even after antiretroviral therapy has controlled it. Now re

NIH-supported Scientists Demonstrate Very Early Formation of SIV Reservoir

July 22, 2014 2:17 pm | by NIH | News | Comments

cientists have generally believed that HIV and its monkey equivalent, SIV, gain a permanent foothold in the body very early after infection, making it difficult to completely eliminate the virus even after antiretroviral therapy has controlled it. Now researchers report that SIV can become entrenched in tissues fewer than 3 days after infection, before the virus is detectable in blood plasma (the liquid part) or blood cells.

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In providing an effective safety and health program effective human resource management is critical. It includes development of accurate job descriptions to take into consideration job duties that may trigger the need for pre-employment evaluations and me

Health and Safety Basics: Workplace Planning and Staffing

July 22, 2014 8:39 am | Articles | Comments

In providing an effective safety and health program effective human resource management is critical. It includes development of accurate job descriptions to take into consideration job duties that may trigger the need for pre-employment evaluations and medical surveillance.

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The Blue Line Cage consists of a wide range of cages, offering flexibility and an automatic watering system. The system offers dual protection for both operators and animals, as well as low maintenance and energy savings. The external self-centering water

Cage with Automatic Watering System

July 22, 2014 8:36 am | Tecniplast S.p.A. | Product Releases | Comments

The Blue Line Cage consists of a wide range of cages, offering flexibility and an automatic watering system.

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Access Technologies Acquires Solomon Scientific Product Lines

July 22, 2014 8:29 am | Access Technologies | News | Comments

Access Technologies, a provider of infusion devices, has announced that it has completed the acquisition of the Solomon Scientific port, catheter and needle product lines.                       

Breeding Zebrafish

July 21, 2014 3:00 pm | by Understanding Animal Research | Videos | Comments

This film shows some of the aspects of zebrafish production and maintenance. Zebrafish embryos, unlike mouse embryos, develop outside the mother's body and are transparent throughout the first few days of life.           

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Pathogen Mishaps Rise as Regulators Stay Clear

July 21, 2014 1:23 pm | by Denise Grady, The New York Times | News | Comments

The recently documented mistakes at federal laboratories involving anthrax, flu and smallpox have incited public outrage at the government’s handling of dangerous pathogens. But the episodes were just a tiny fraction of the hundreds that have occurred in recent years across a sprawling web of academic, commercial and government labs that operate without clear national standards or oversight, federal reports show.

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DNA Mapping Technique Could Reduce Mice Needed for Research

July 21, 2014 1:09 pm | by BBSRC | News | Comments

Researchers have developed a powerful new single-cell technique to help investigate how the environment affects our development and the traits we inherit from our parents. This approach will boost understanding of embryonic development, could enhance clinical applications like cancer therapy and fertility treatments, and has the potential to reduce the number of mice currently needed for this research.

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Immune Cell Role in Intestinal Movement Seen in Mice

July 21, 2014 12:56 pm | by Pennsylvania State Univ. | News | Comments

Learning the role of immune-system cells in healthy digestive tracts and how they interact with neighboring nerve cells may lead to new treatments for irritable bowel syndrome (IBS).                   

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Fish Oil Reduces Alcoholic Neurodegeneration in Rats

July 21, 2014 12:46 pm | by Loyola Univ. Health Sciences | News | Comments

Omega-3 fish oil might help protect against alcohol-related neurodamage and the risk of eventual dementia, according to a study.                                   

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Can Life Experience Shape the Genes We Pass Along?

July 21, 2014 8:12 am | by Helen Kelly and Laura E. Kelly | Articles | Comments

At one time scientists described DNA as fate. Now they know that DNA is potential, because experience—principally early life experience—plays a big part in how genes behave. The experience we’re talking about ranges from how your parents lived before you were conceived to how your mother felt and what she ate during pregnancy...

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Small Animal Imaging System

July 21, 2014 8:10 am | PerkinElmer | Product Releases | Comments

The IVIS SpectrumBL high-throughput 2D and 3D optical imaging system can simultaneously image up to 10 mice with full gas anesthesia incorporation along with ultra-high sensitivity to support bioluminescence, chemiluminescence, and Cerenkov radioisotopic imaging.

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Cat Parasite Fights Cancer

July 18, 2014 4:48 pm | by Norris Cotton Cancer Center | News | Comments

From the litter box to the laboratory, a microscopic organism native to cats shows promise in treating cancer. A mutated strain of T. gondii reprograms the natural power of the immune system to kill cells.             

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Obesity, Inflammation and Insulin Resistance Linked in Mice

July 18, 2014 11:45 am | by Susan Gammon, Sanford-Burnham Medical Research Institute | News | Comments

A study has identified a new signal that triggers the events leading to insulin resistance in obesity. The signal causes inflammation in adipose tissue and leads to metabolic disease, suggesting that blocking this signal may protect against the development of metabolic disease, type 2 diabetes, and other disorders caused by obesity-linked inflammation.

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Viral Relics Show Cancer's 'Footprint' on Our Evolution

July 18, 2014 11:29 am | by Univ. of Oxford | News | Comments

Cancer has left its "footprint" on our evolution, according to a study which examined how the relics of ancient viruses are preserved in the genomes of 38 mammal species.                       

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