The leading source for today's research animal facilities.
Subscribe to Controlled Environments All

The Lead

Spotlight on the Microbiome in Clinical Practice

July 30, 2015 | by Helen Kelly | Articles | Comments

Professor Jeremy Nicholson, a Professor of Biological Chemistry, Head of the Department of Surgery and Cancer, at Imperial College London, says that accurately measuring the biological origins of disease begins with the microbiome rather than with the genome.




July 31, 2015 10:32 am | by Rees Scientific | Rees Scientific | Product Releases | Comments

ReesCloud offers a cloud based, cost effective tool to monitor refrigeration, cold storage laboratory equipment and a wide range of critical environments. There is no software, PC or server required from the client, the only necessity is a data connection. Users have the ability to view the status of their equipment via an app or a browser.

Surprising Similarity in Fly and Mouse Motion Vision

July 31, 2015 10:31 am | News | Comments

At first glance, the eyes of mammals and those of insects do not seem to have much in common. However, a comparison of the neural circuits for detecting motion shows surprising parallels between flies and mice.


Depression Starts as a Gut Feeling

July 30, 2015 9:49 am | by Amanda Boundris, McMaster University | News | Comments

Bacteria in your gut play an important role in inducing anxiety and depression, scientists from the Farncombe Family Digestive Health Research Institute at McMaster University have discovered. Their study, published today in Nature Communications, is the first to explore the role of intestinal microbiota in altered behavior that comes from early life stress.


Where Memory is Encoded and Retrieved

July 30, 2015 9:40 am | News | Comments

Are the same regions and even the same cells of the brain area called hippocampus involved in encoding and retrieving memories or are different areas of this structure engaged? This question has kept neuroscientists busy for a long time. Researchers at the Mercator Research Group "Structure of Memory" at RUB have now found out that the same brain cells exhibit activity in both processes.


Experimental MERS Vaccine Shows Promise in Animal Studies

July 30, 2015 9:31 am | News | Comments

A two-step regimen of experimental vaccines against Middle East respiratory syndrome (MERS) prompted immune responses in mice and rhesus macaques, report National Institutes of Health scientists who designed the vaccines.


Low Dose Lithium Limits Side Effects of Common Parkinson's Drug in Mouse Study

July 30, 2015 9:21 am | by Elizabeth Doughman, Editor-in-Chief | News | Comments

Low dose lithium reduced involuntary motor movements in a mouse model of Parkison's disease (PD), according to a study published online in Brain Research. Involuntary motor movements are a common side effect of the medications used to treat PD.


Working Together to Reduce ‘Severe’ Suffering—It Can Be Done!

July 30, 2015 9:21 am | by Penny Hawkins BSc, PhD | Blogs | Comments

While the debate about animal research and testing can become pretty heated in the public arena, the research community and scientific animal welfare organizations have a long history of identifying common ground and working constructively together to replace, reduce and refine animal use.


Overcoming Compassion Fatigue in the Biomedical Lab

July 30, 2015 9:19 am | by Helen Kelly | Articles | Comments

It is not surprising to find that in an animal research laboratory, first-line caretakers can be ambushed and even overcome by feelings of sadness, loss and grief such that they become disappointed, dejected, disillusioned, exhausted, or burned out.


Small Genetic Differences Could Mean Life-and-death for Gut Infection

July 29, 2015 10:16 am | News | Comments

Considering how many microorganisms we ingest each day, our gut has an extensive and well-developed immune system. This defense is involved in acute and chronic gut diseases, but it varies dramatically among people. A persistent question is how our genetic make-up affects our gut’s ability to fight infections.


New Treatment Options for a Fatal Leukemia

July 29, 2015 10:07 am | News | Comments

In industrialized countries like Switzerland acute lymphoblastic leukemia represents the most frequent type of cancer in children. Together with international researchers, a pediatric oncologist from the University of Zurich has now succeeded in decoding a rare but always fatal subtype of this leukemia and in obtaining pointers for new therapeutic possibilities.


Major European Mouse Study Reveals the Role of Genes in Disease

July 29, 2015 9:58 am | News | Comments

The functions of around 150 genes have been discovered by scientists across Europe in a major initiative to try to understand the part they play in disease and biology.


Exercise Mimicking Molecule May Help Treat Diabetes and Obesity

July 29, 2015 9:47 am | News | Comments

Scientists from the University of Southampton have developed a molecule that acts as an exercise mimic, which could potentially help treat type 2 diabetes and obesity.


MicroFlow I Workstation

July 29, 2015 9:45 am | by HEMCO Corporation | HEMCO Corporation | Product Releases | Comments

The MicroFlow I Workstation is designed to collect small amounts of non-hazardous fumes and particulate. The workstation is self contained and can be easily moved from station to station. Completely self contained with integral recessed work surface to contain spills. Clear hood surround with safety viewing sash for user. Sash can be conformed for use with a microscope. Variable speed fan control provides the option of high and medium speeds, or low...

A Novel Liquid Diet for Use in Swine

July 29, 2015 9:23 am | by Amy F. Kilpatrick, RLATg, CVT CPIA, Misty J. Williams-Fritze, DVM, MS, DACLAM, and Alison Hayward, DVM | Articles | Comments

According to the Guide and Animal Welfare Act Regulations, a diet must be provided that is palatable, uncontaminated, and meets the nutritional needs of the research animals.Modifying diets involves meeting the requirements of the study as well as the needs of the animal. Swine are a common animal model used in gastrointestinal research due to their anatomical and physiological similarities to humans.

 Cancer can be caused solely by protein imbalances within cells, a study of ovarian cancer has found. The discovery is a major breakthrough because, until now, genetic aberrations have been seen as the main cause of almost all cancer.

Non-Genetic Cancer Mechanism Discovered in Mice

July 28, 2015 12:40 pm | by University of Leeds | News | Comments

Cancer can be caused solely by protein imbalances within cells, a study of ovarian cancer has found. The discovery is a major breakthrough because, until now, genetic aberrations have been seen as the main cause of almost all cancer.



You may login with either your assigned username or your e-mail address.
The password field is case sensitive.