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Tips for Standardization during Research Studies

December 18, 2014 | by Elizabeth Doughman, Editor-in-Chief | Articles | Comments

In a November 2014 survey, ALN World asked respondents to share what their facility does to limit variables during research studies. Uniformity—from housing to animals to data collection equipment—was continually stressed throughout the answers.

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Llama Antibodies Neutralize HIV/AIDS

December 19, 2014 10:16 am | News | Comments

Most vaccines work by inducing an immune response characterized by neutralizing antibodies against the respective pathogen. A new study reports that a combination of antibodies from llamas can neutralize a wide range of circulating HIV viruses.

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Primate Cage Allows Socialization

December 19, 2014 9:27 am | Lenderking Caging Products | Product Releases | Comments

The “Rabbit Hole” (patent pending) socializes two primates vertically, with just a slight increase in the cage’s footprint. This easy to use system has no panels to remove and will also act as a foraging system. When also used in the lower cage compartment it can be a foraging system or a pool. Primates will then use the entire vertical space of their cage which could increase their psychological well-being.

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Fruit Fly Lab to Study Space's Impact on Infection

December 18, 2014 11:44 am | by Gianine M. Figliozzi | News | Comments

The most advanced system to date for studying fruit flies in space, NASA’s Fruit Fly Lab, is making its debut aboard the International Space Station. The Fruit Fly Lab-01 mission, planned to launch to the station in December aboard SpaceX's fifth commercial resupply services (CRS) mission, is the first of a series of fruit fly investigations NASA plans to conduct.

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Mistletoe Could Fight Obesity-related Liver Disease

December 18, 2014 11:28 am | News | Comments

Mistletoe hanging in doorways announces that the holidays are just around the corner. For some people, however, the symbolic plant might one day represent more than a kiss at Christmas time: It may mean better liver health.     

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Epigenetic Changes in Brain Tied to Autism

December 18, 2014 10:03 am | News | Comments

Biochemists from NYU Langone Medical Center found that epigenetic changes in mice and laboratory experiments remove the blocking mechanism of a protein complex long known for gene suppression, and transitions the complex to a gene activating role instead.

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Mouse Study Finds Stem Cells Faulty in Duchenne Muscular Dystrophy

December 18, 2014 9:50 am | by Krista Conger | News | Comments

Like human patients, mice with a form of Duchenne muscular dystrophy undergo progressive muscle degeneration and accumulate connective tissue as they age. Now, researchers at the Stanford University School of Medicine have found that the fault may lie at least partly in the stem cells that surround the muscle fibers.

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Multiple Allergic Reactions Traced To Single Protein

December 18, 2014 9:36 am | News | Comments

Through research in mice, Johns Hopkins and University of Alberta researchers have identified a single protein as the root of painful and dangerous allergic reactions to a range of medications and other substances. If a new drug can be found that targets the problematic protein, it could help smooth treatment for patients with conditions ranging from prostate cancer to diabetes to HIV.

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Medical Research Software

December 18, 2014 9:18 am | a-tune software AG, a-tune software, Inc. | Product Releases | Comments

The software suite, tick@lab delivers compliance management for IACUC, IRB, and IBC. Other tick@lab applications are available for Protocol Management, Transgenic Breeding, Capacity Planning, Task Management, Accounting, Facility Management and Vet Records.

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Whether an odor is pleasant or disgusting to an organism is not just a matter of taste. Often, an organism’s survival depends on its ability to make just such a discrimination. However, odor sources can also be signs of lethal hazards. Scientists have now

Lateral Horn in Fruit Fly Brain Distinguishes Good Smells from Bad

December 17, 2014 11:56 am | by Max Planck Institute for Chemical Ecology | News | Comments

Whether an odor is pleasant or disgusting to an organism is not just a matter of taste. Often, an organism’s survival depends on its ability to make just such a discrimination. However, odor sources can also be signs of lethal hazards. Scientists have now found that in fruit flies, the quality and intensity of odors can be mapped in the so-called lateral horn.

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As the main component of connective tissue in the body, fibroblasts are the most common type of cell. Taking advantage of that ready availability, scientists have discovered a way to repurpose fibroblasts into functional melanocytes, the body's pigment-pr

New Technology Reprograms Skin Fibroblasts in Mice

December 17, 2014 11:43 am | by Penn Medicine | News | Comments

As the main component of connective tissue in the body, fibroblasts are the most common type of cell. Taking advantage of that ready availability, scientists have discovered a way to repurpose fibroblasts into functional melanocytes, the body's pigment-producing cells. The technique has immediate and important implications for developing new cell-based treatments.

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Extra vitamin E protected older mice from a bacterial infection that commonly causes pneumonia. Microbiologists and nutrition researchers report that the extra vitamin E helped regulate the mice’s immune system. The findings show promise for studies inves

Vitamin E Protects Older Mice from Getting Pneumonia

December 17, 2014 11:33 am | by Tufts University | News | Comments

Extra vitamin E protected older mice from a bacterial infection that commonly causes pneumonia. Microbiologists and nutrition researchers report that the extra vitamin E helped regulate the mice’s immune system. The findings show promise for studies investigating the effects of vitamin E and infection in humans.

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Scientists have been able to shed light on important neural circuitry involved in the prey capture behavior exhibited by young zebrafish. The findings show that neurons in the retina of the eye already filter out prey objects from other environmental sign

Zebrafish Retina Wired for Prey

December 17, 2014 11:19 am | by Max-Planck-Gesellschaft | News | Comments

Scientists have been able to shed light on important neural circuitry involved in the prey capture behavior exhibited by young zebrafish. The findings show that neurons in the retina of the eye already filter out prey objects from other environmental signals.

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Pentair Aquatic Eco-Systems Aquires PR Aqua

December 17, 2014 10:58 am | Pentair Aquatic Eco-Systems, Inc. | News | Comments

Pentair Aquatic Eco-Systems, Inc. has acquired PR Aqua Supplies Ltd., a leading aquaculture design and equipment provider based in Nanaimo, BC, Canada.                            

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To create the ideal vivarium environment—one that eliminates unsafe work practices, ensures maximum productivity, and fosters a people-friendly and caring atmosphere when working with animals—requires an understanding of the behaviors of the people who wo

Five Key Concepts for Creating People-Friendly Vivarium Environments

December 17, 2014 8:47 am | by George Kemper | Articles | Comments

To create the ideal vivarium environment—one that eliminates unsafe work practices, ensures maximum productivity, and fosters a people-friendly and caring atmosphere when working with animals—requires an understanding of the behaviors of the people who work in the vivarium. Designers who understand this premise and are involved in all phases of the OSHA strategies are invaluable partners in vivarium design.

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Mobile Aquatic Systems

December 17, 2014 8:31 am | Thoren Caging Systems, Inc. | Product Releases | Comments

The Mobile Aquatic system has changed the way researchers can have access to their fish within the lab. It also provides the ideal teaching environment for university labs. 

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