Professor Jeremy Nicholson, a Professor of Biological Chemistry, Head of the Department of Surgery and Cancer, at Imperial College London, says that accurately measuring the biological origins of disease begins with the microbiome rather than with the genome.
The protein RGS2 is vital for healthy egg-sperm union in mice, according to a new study from...
After infection with leishmaniasis, the skin retains a population of T cells that remember how...
With many types of cancers, early detection offers the best hope for survival. However, research...
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At first glance, the eyes of mammals and those of insects do not seem to have much in common. However, a comparison of the neural circuits for detecting motion shows surprising parallels between flies and mice.
Bacteria in your gut play an important role in inducing anxiety and depression, scientists from the Farncombe Family Digestive Health Research Institute at McMaster University have discovered. Their study, published today in Nature Communications, is the first to explore the role of intestinal microbiota in altered behavior that comes from early life stress.
Are the same regions and even the same cells of the brain area called hippocampus involved in encoding and retrieving memories or are different areas of this structure engaged? This question has kept neuroscientists busy for a long time. Researchers at the Mercator Research Group "Structure of Memory" at RUB have now found out that the same brain cells exhibit activity in both processes.
A two-step regimen of experimental vaccines against Middle East respiratory syndrome (MERS) prompted immune responses in mice and rhesus macaques, report National Institutes of Health scientists who designed the vaccines.
Low dose lithium reduced involuntary motor movements in a mouse model of Parkison's disease (PD), according to a study published online in Brain Research. Involuntary motor movements are a common side effect of the medications used to treat PD.
While the debate about animal research and testing can become pretty heated in the public arena, the research community and scientific animal welfare organizations have a long history of identifying common ground and working constructively together to replace, reduce and refine animal use.
It is not surprising to find that in an animal research laboratory, first-line caretakers can be ambushed and even overcome by feelings of sadness, loss and grief such that they become disappointed, dejected, disillusioned, exhausted, or burned out.
Considering how many microorganisms we ingest each day, our gut has an extensive and well-developed immune system. This defense is involved in acute and chronic gut diseases, but it varies dramatically among people. A persistent question is how our genetic make-up affects our gut’s ability to fight infections.
In industrialized countries like Switzerland acute lymphoblastic leukemia represents the most frequent type of cancer in children. Together with international researchers, a pediatric oncologist from the University of Zurich has now succeeded in decoding a rare but always fatal subtype of this leukemia and in obtaining pointers for new therapeutic possibilities.
The functions of around 150 genes have been discovered by scientists across Europe in a major initiative to try to understand the part they play in disease and biology.
Scientists from the University of Southampton have developed a molecule that acts as an exercise mimic, which could potentially help treat type 2 diabetes and obesity.
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According to the Guide and Animal Welfare Act Regulations, a diet must be provided that is palatable, uncontaminated, and meets the nutritional needs of the research animals.Modifying diets involves meeting the requirements of the study as well as the needs of the animal. Swine are a common animal model used in gastrointestinal research due to their anatomical and physiological similarities to humans.
Cancer can be caused solely by protein imbalances within cells, a study of ovarian cancer has found. The discovery is a major breakthrough because, until now, genetic aberrations have been seen as the main cause of almost all cancer.