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Process Improvement Concepts

March 4, 2015 | by Stacy Pritt | Articles | Comments

With limited resources, managers and staff often turn to methods for improving productivity and efficiency within the animal care program. Applying the concepts of continuous process improvement can enable facilities to become more productive and efficient in a sustainable manner.

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Majority of Lab Users Want Input on Vivarium Design Process

March 4, 2015 10:49 am | by Elizabeth Doughman, Editor-in-Chief | Articles | Comments

ALN recently asked subscribers what role they want architects/lab designers to play in the design/build or renovation process. Click here to see the results.

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A team of investigators have developed an antibody which has proven 100 percent protective against the virus in two species of animal models.

Compound Protects 100% of Ferrets, Mice From H5N1

March 4, 2015 9:23 am | by American Society for Microbiology | News | Comments

A team of investigators have developed an antibody which has proven 100 percent protective against the virus in two species of animal models.

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Biologists have determined how the loss of a gene in male mice results in the premature exhaustion of their fertility. Their fundamental new insights into the complex process of sperm generation may have direct applications to a similar loss of fertility

Mutation Causes Early Loss of Sperm Supply in Mice

March 4, 2015 9:09 am | News | Comments

Biologists have determined how the loss of a gene in male mice results in the premature exhaustion of their fertility. Their fundamental new insights into the complex process of sperm generation may have direct applications to a similar loss of fertility in men.

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Highlighting a potential target in the treatment of multiple sclerosis (MS) and Alzheimer’s disease, new research suggests that triggering a protein found on the surface of brain cells may help slow the progression of these and other neurological diseases

New Alzheimer's, Multiple Sclerosis Target Identified in Mice

March 4, 2015 9:03 am | by Michael C. Purdy, Washington University in St. Louis | News | Comments

Highlighting a potential target in the treatment of multiple sclerosis (MS) and Alzheimer’s disease, new research suggests that triggering a protein found on the surface of brain cells may help slow the progression of these and other neurological diseases.

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ALZET Osmotic Pumps are small, implantable devices for continuous delivery of test agents in mice, rats and larger animals. They are a reliable and convenient alternative to repetitive injections, enabling accurate dosing while eliminating frequent animal

Osmotic Pumps

March 4, 2015 8:39 am | ALZET Osmotic Pumps/DURECT Corporation | Product Releases | Comments

ALZET Osmotic Pumps are small, implantable devices for continuous delivery of test agents in mice, rats and larger animals. They are a reliable and convenient alternative to repetitive injections, enabling accurate dosing while eliminating frequent animal handling and stress. They are easy to use by lab personnel: fill with test solution, implant, and infusion starts automatically for durations up to six weeks.

Researchers have identified a novel role for a signaling mechanism in lung cells that permanently places them into a state of suspended animation called senescence. Alive but unable to do much of anything, including divide, senescent cells cannot become c

Halting Cell Division Protects Lung Cells in Mice From Cancer

March 3, 2015 11:50 am | by Sharon Parmet, University of Illinois | News | Comments

Researchers have identified a novel role for a signaling mechanism in lung cells that permanently places them into a state of suspended animation called senescence. Alive but unable to do much of anything, including divide, senescent cells cannot become cancerous. Drugs that can induce senescence through this signaling pathway would represent a new class of chemotherapy.

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What do a human colon, septic tank, copper nanoparticles and zebrafish have in common? They were the key components used by researchers to study the impact copper nanoparticles, which are found in everything from paint to cosmetics, have on organisms inad

Impact of Copper Nanoparticles on Zebrafish Studied in the Lab

March 3, 2015 11:27 am | by Sean Nealon, University of California, Irvine | News | Comments

What do a human colon, septic tank, copper nanoparticles and zebrafish have in common? They were the key components used by researchers to study the impact copper nanoparticles, which are found in everything from paint to cosmetics, have on organisms inadvertently exposed to them.

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Chemotherapy often shrinks tumors at first, but as cancer cells become resistant to drug treatment, tumors can grow back. A new nanodevice can help overcome that by first blocking the gene that confers drug resistance, then launching a new chemotherapy at

Nanodevice Defeats Drug Resistance in Mice

March 3, 2015 11:03 am | by Anne Trafton, MIT | News | Comments

Chemotherapy often shrinks tumors at first, but as cancer cells become resistant to drug treatment, tumors can grow back. A new nanodevice can help overcome that by first blocking the gene that confers drug resistance, then launching a new chemotherapy attack against the disarmed tumors.

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In a new study, brain scientists have mapped changes in communication between nerve cells as rats learned to make specific decisions in response to particular sounds. The team then used this map to accurately predict the rats’ reactions. These results add

Scientists Map Memorable Tunes in the Rat Brain

March 3, 2015 10:53 am | by NIH | News | Comments

In a new study, brain scientists have mapped changes in communication between nerve cells as rats learned to make specific decisions in response to particular sounds. The team then used this map to accurately predict the rats’ reactions. These results add to our understanding of how the brain processes sensations and forms memories to inform behavior.

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Why is Workplace Culture Important?

March 3, 2015 8:48 am | Articles | Comments

Culture matters. It is the glue that holds a company together by providing guides as to what employees should say and do. It also helps employees to commit to something larger themselves. Members of a culture develop a shared sense of identity—and that identity serves to differentiate them from other organizations in the same industry or profession.

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Common Flame Retardant Causes Obesity in Rats

March 3, 2015 8:38 am | by Elizabeth Doughman, Editor-in-Chief | News | Comments

Chemicals used as synthetic flame retardants in common household items such as couches, carpet padding, and electronics have been found to cause metabolic and liver problems in laboratory rats. These problems can lead to insulin resistance, a major cause of obesity, according to a new study from the University of New Hampshire.

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Seattle-based Aquatic Enterprises Inc has announced its twenty-fifth year as a key player in the aquatic animal housing industry. Achieved using the philosophy of constant innovation and customer awareness, Aquatic Enterprises has grown from servicing res

Aquatic Enterprises Celebrates 25 Years

March 3, 2015 8:37 am | Aquatic Enterprises, Inc. | News | Comments

Seattle-based Aquatic Enterprises Inc has announced its twenty-fifth year as a key player in the aquatic animal housing industry. Aquatic Enterprises has grown from servicing residential fish tanks and ponds to manufacturing state-of-the art equipment for universities and schools, research institutes, public aquariums, fish hatcheries, seafood retailers and seafood wholesalers.

Corrosion of stainless equipment is a significant problem. Corroded surfaces are difficult to clean and disinfect because the rough surfaces do not allow good wiping contact and provide places for bacteria to accumulate. ABRATEC abrasive cloths remove sur

Abrasive Cloths

March 3, 2015 8:35 am | by Contec, Inc. | Contec, Inc. | Product Releases | Comments

Corrosion of stainless equipment is a significant problem. Corroded surfaces are difficult to clean and disinfect because the rough surfaces do not allow good wiping contact and provide places for bacteria to accumulate. ABRATEC abrasive cloths remove surface rust and residue from stainless steel to make equipment look new. 

A key part of the brain involved with decision making, the striatum, appears to operate hierarchically – much like a traditional corporation with executives, middle managers and employees.

Brain's Decision-Making Structure Seen in Rats

March 2, 2015 10:52 am | by OIST | News | Comments

A key part of the brain involved with decision making, the striatum, appears to operate hierarchically – much like a traditional corporation with executives, middle managers and employees.

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A newly characterized group of pharmacological compounds block both the inflammation and nerve cell damage seen in mouse models of multiple sclerosis, according to a recent study.

Compounds Protect Against MS Nerve Damage in Mouse Models

March 2, 2015 10:32 am | by Mount Sinai Health System | News | Comments

A newly characterized group of pharmacological compounds block both the inflammation and nerve cell damage seen in mouse models of multiple sclerosis, according to a recent study.

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