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The Lead

To Sneeze or Not to Sneeze: Lab Animal Allergens

October 8, 2015 | by Cheryl Pater, BS, RVT, RLATG, CMAR | Articles | Comments

Lab animal allergens have become a very serious safety and health issue.



Decoding What Goes Wrong in Arthritis

October 8, 2015 11:22 am | News | Comments

Scientists have discovered what they believe has the potential to prevent the onset of an aggressive and hard-to-treat form of rheumatoid arthritis. In a new study, a team of immunologists describe how an immune system protein - interleukin-27 - regulates the inflammatory process in lymphoid-rich rheumatoid arthritis, which causes the characteristic symptoms of swollen and painful joints.


Modular Lab Furniture Systems

October 8, 2015 9:45 am | by HEMCO Corporation | HEMCO Corporation | Product Releases | Comments

UniLine Furniture offerings include Base Cabinets, Wall Cabinets, Countertops, Sinks, Fixtures, Base-Tables, Mobile Work Stations, Specialty Storage Cabinets and Peg Boards. Our Uniline Casework Groupings are designed to incorporate our most popular casework styles in a complete package. Our services can also include a complete turnkey installation.

Achieving Sustainability in Vivariums

October 7, 2015 4:32 pm | by George Kemper and Christina Willis, AIA, LEED AP | Articles | Comments

Many organizations commit to going green by reducing energy, water, and waste. This is a goal for vivariums too, even though they face more hurdles in achieving sustainability due to the need to adhere to the many rules and regulations set forth by the Guide for the Care and Use of Laboratory Animals (the Guide), building codes, and funding agencies.


AAALAC International Celebrates Its 50th Anniversary

October 7, 2015 4:09 pm | by Christian E. Newcomer, VMD, MS, DACLAM | Articles | Comments

In 2015, AAALAC International is celebrating its 50th anniversary. We are proud of our success in promoting research animal welfare, creating an environment for productive scientific inquiry with research animals, and allaying some of the public concern surrounding the use of animals.


Do's and Don'ts of Developing an NIH Grant Application

October 7, 2015 3:56 pm | by Stephanie J. Murphy, VMD, Ph.D. and Franziska B. Grieder, DVM, Ph.D. | Articles | Comments

NIH supports a wide variety of grants in the form of different grant mechanisms. A scientist who wants to apply for funding needs to understand the different NIH funding mechanisms before writing an application and the steps for applying for any given mechanism (e.g., a letter of intent or an approval letter may be required).


Connect, Collaborate, and Innovate at the 2016 TurnKey Conference

October 7, 2015 3:36 pm | by Elizabeth Doughman, Editor-in-Chief | Articles | Comments

The 13th annual TurnKey Conference will be held May 24-25, 2016 at the Gaylord National Harbor Resort and Convention Center in Washington, DC. The theme for this year’s event is Connect. Collaborate. Innovate. Here’s how we’re really embracing this theme for our 2016 Conference.


Horse Illness Shares Signs of Human Disease

October 7, 2015 11:04 am | News | Comments

Horses with a rare nerve condition have similar signs of disease as people with conditions such as Alzheimer’s, a study has found.


Finches Offer Researchers a New Tool to Study Huntington's Disease

October 7, 2015 10:57 am | News | Comments

Many neurological disorders can rob someone of the ability to speak clearly, causing them to stutter, mispronounce words, and struggle to put together coherent sentences. Recent work may give researchers a new tool to better study these vocal and speech impairments, particularly in Huntington’s disease.


Scientists Test New Gene Therapy for Vision Loss from a Mitochondrial Disease

October 7, 2015 10:39 am | News | Comments

Researchers funded by the National Institutes of Health have developed a novel mouse model for the vision disorder Leber hereditary optic neuropathy (LHON), and found that they can use gene therapy to improve visual function in the mice. LHON is one of many diseases tied to gene mutations that damage the tiny energy factories that power our cells, called mitochondria.


Nanoparticulate Carbon Black Particles are the Tiny Culprits that Start Emphysema

October 7, 2015 10:17 am | News | Comments

When pathologists perform autopsies on smokers who died with severe emphysema, they find that lungs are black in appearance. Until recently, researchers and physicians could only guess at the composition of the material that gave the black color to the lungs of smokers.


Gut Development During Mouse Infancy Key to Lifelong Health

October 7, 2015 9:22 am | by Elizabeth Doughman, Editor-in-Chief | News | Comments

The suckling period in mice is crucial for the development of gut health, according to a new study published in the journal, Genome Biology. This time period is critical because of the number of epigenetic changes that occur during the development of stem cells in the intestine.  


What is Really in our Drinking Water?

October 7, 2015 9:22 am | by Marianne Metzger | Articles | Comments

Many people take it for granted that they can turn on a faucet and get clean, safe water to drink. For the most part, this is true. It really depends on your definition of clean and safe. For those working with animals in a research capacity, this assumption could be a mistake that can drastically affect the outcome of important study results.


High-fructose Diet Hampers Recovery from Traumatic Brain Injury

October 6, 2015 11:17 am | by Elaine Schmidt, UCLA | News | Comments

A diet high in processed fructose sabotages rats’ brains’ ability to heal after head trauma, UCLA neuroscientists report.


Researchers Create Self-propelled Powder to Stop Bleeding

October 6, 2015 11:04 am | Videos | Comments

UBC researchers have created the first self-propelled particles capable of delivering coagulants against the flow of blood to treat severe bleeding, a potentially huge advancement in trauma care.

Scientists Closer to Controlling Body Temperature in Response to 'Fight or Flight'

October 6, 2015 10:23 am | News | Comments

New research published online in The FASEB Journal suggests that the fight or flight response that we experience in stressful situations may be controlled by a protein called TRPV1. In the mouse study, researchers found that TRPV1 controls the nerves that release noradrenaline and affect core body temperature. This opens the doors for the development of new strategies to treat the effects of stress on the body.



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