The use of specific pathogen free (SPF) laboratory animals in biomedical research increases demand for sterilized feeds for breeding and maintenance purposes. In many breeding units autoclave sterilization of commercial diets is preferentially employed. This relatively inexpensive and convenient method comprises heat, pressure, and steam treatment of pelleted feeds.
Looking across evolutionary time and the genomic landscapes of humans and mice, an international...
A new study in mice shows that our natural gut-residing microbes can influence the integrity of...
Chemists have developed new nanoparticles that can simultaneously perform magnetic resonance...
Harvard Apparatus surgical instrument kits, configured from the Harvard Apparatus high quality surgical tool line, combine the most popular pieces for both general and specific surgical applications.
Researchers have found that a growth factor can regenerate damaged peripheral nerves without causing the growth of new blood vessels — making it a unique candidate to treat nerve damage in areas of the body where the proliferation of blood vessels would be a drawback.
HEMCO Modular CleanLabs feature a modular construction design that is cost effective and time efficient compared to traditional construction. An entire laboratory workspace is pre-engineered including the structure and the lab furniture/fume hoods to outfit the interior.
By manipulating the circadian clocks of Siberian hamsters, scientists may have identified a brain structure that disrupts memory when circadian rhythms fall apart, as they often do in patients with neurodegenerative diseases such as Alzheimer's.
In what is likely to be a major step forward in the study of influenza, cystic fibrosis and other human diseases, an international research effort has sequenced the ferret genome. The sequence was then used to analyze how the flu and cystic fibrosis affect respiratory tissues at the cellular level.
It all started in 2008 at the University of North Carolina (UNC) School of Medicine. The goal: attract top investigators -- Ph.D.s, Ph.D. candidates, professors, and post grads — and fundamentally advance knowledge of cancer and other complex diseases. This is not a classroom building; it is a research facility.
For over a decade, animal care guidelines have emphasized the need for continuous, electronic monitoring of vivariums and related facilities. To meet this need, many products offer continuous monitoring and reporting of environmental conditions such as temperature, humidity, airflow, and light levels. Unfortunately, these can be costly to install and operate, which is beyond the resources of many facilities.
The Sarstedt S-Monovette® is an enclosed multiple-sampling blood collection system designed with safety in mind. All tubes are plastic with screw caps, which minimizes the risk of breakage and aerosol formation when caps are removed.
Researchers have discovered how a previously unknown hormone serves as a messenger from fat cells to the liver and are investigating the potential of developing a new treatment for metabolic disorders.
Scientists have identified a novel delivery platform by which an antisense molecule — akin to the mirror image of the microRNA — can be used to exploit a unique feature of the tumor microenvironment and thereby gain access to cancer cells.
A team of scientists have found that a particular set of cells in a small region of the brain are responsible for memory problems after sleep loss. By selectively increasing levels of a signaling molecule in these cells, the researchers prevented mice from having memory deficits.
Scientists from Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) in Japan have developed an advanced imaging system to identify cells responsible for storing memory within a tiny worm. Their study not only offers a new way to identify molecular substrates of memory but may also one day lead to understanding how memory loss occurs in humans.
The ALN November/December 2014 digital edition is here! Click to start reading.
A team of researchers from Johns Hopkins Medicine has discovered a receptor on blood vessels that causes the vessel to relax in response to light, making it potentially useful in treating vascular diseases. In addition, researchers discovered a previously unknown mechanism by which blood vessel function is regulated through light of a specific wavelength.
Researchers have developed new insight into a rare but deadly brain infection, called progressive multifocal leukoencephalopathy. This disease – which is caused by the JC virus – is most frequently found in people with suppressed immune systems and, until now, scientists have had no effective way to study it or test new treatments.